CP 55,940
Tocris Bioscience, part of Bio-Techne | Catalog # 0949
Potent and non-selective CB agonist
Discontinued Product
0949 has been discontinued.
View all Non-selective Cannabinoid Receptor Agonists products.
Key Product Details
Description
Potent and non-selective CB agonist
Product Description
Cannabinoid agonist which is considerably more potent than Δ9-THC in both behavioral tests and receptor binding assays. Displays high and roughly equal affinity for both central and peripheral cannabinoid receptors (Ki = 0.6 - 5.0 and 0.7 - 2.6 nM at CB1 and CB2 respectively; EC50 values are 0.2, 0.3 and 5 nM at CB1, CB2 and GRP55 respectively).Licensing Information
Sold for research purposes under agreement from Pfizer Inc.Product Specifications
Molecular Weight
376.58
Formula
C24H40O3
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol
CAS Number
83002-04-4
PubChem ID
104895
InChI Key
YNZFFALZMRAPHQ-SYYKKAFVSA-N
SMILES
O[C@H]1C[C@@H]([C@]2=CC=C(C(C)(C)CCCCCC)C=C2O)[C@H](CCCO)CC1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 37.66 | 100 | |
| Ethanol | 37.66 | 100 |
Preparing Stock Solutions
for CP 55,940
The following data is based on the product molecular weight 376.58
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.66 mL | 13.28 mL | 26.55 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.31 mL |
| 10 mM | 0.27 mL | 1.33 mL | 2.66 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.53 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Avdesh Corticosteroid dependent and independent effects of a cannabinoid agonist on core temperature, motor activity, and prepulse inhibition of the acoustic startle reflex in Wistar rats. Psychopharmacology 2011 PMID: 21947354
- Thomas Comparative receptor binding analyses of cannabinoid agonists and antagonists. J.Pharmacol.Exp.Ther. 1998 PMID: 9536023
- Wiley Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats. Neuropharmacology 1995 PMID: 7566504
- Griffin Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes. J.Pharmacol.Exp.Ther. 1998 PMID: 9580597
Product Specific Notices for CP 55,940
For research use only
Loading...
Loading...