Clotrimazole

Tocris Bioscience, part of Bio-Techne | Catalog # 4096

Cytochrome P450 inhibitor; antifungal
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Key Product Details

Description

Cytochrome P450 inhibitor; antifungal

Alternative Names

CLT

View all Cytochrome P450 Inhibitors »

Product Description

Clotrimazole is an imidazole antimycotic and cytochrome P450 inhibitor. Inhibits Ca2+-activated K+ current (IC50 = 3 μM) and L-type Ca2+ current; increases the firing rate of action potentials. Exhibits antiproliferative activity in vitro and in vivo. Also an inverse agonist of the human constitutive androstane receptor (hCAR).

Product Specifications

Molecular Weight

344.84

Formula

C22H17ClN2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

1-(2-Chloro-α,α-diphenylbenzyl)imidazole

CAS Number

23593-75-1

PubChem ID

2812

InChI Key

VNFPBHJOKIVQEB-UHFFFAOYSA-N

SMILES

ClC1=CC=CC=C1C(C3=CC=CC=C3)(C4=CC=CC=C4)N2C=CN=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 25.86 75
Ethanol 34.48 100

Preparing Stock Solutions for Clotrimazole

The following data is based on the product molecular weight 344.84

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.90 mL 14.50 mL 29.00 mL
5 mM 0.58 mL 2.90 mL 5.80 mL
10 mM 0.29 mL 1.45 mL 2.90 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Calculators

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Product Documents for Clotrimazole

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Clotrimazole

For research use only

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