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Clemastine fumarate

Tocris Bioscience, part of Bio-Techne | Catalog # 1453

H1 antagonist
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1453/100

Key Product Details

Description

H1 antagonist

Product Description

Clemastine fumarate is a h1-receptor antagonist. Enhances differentiation of oligodendrocyte progenitor cells into myelin basic protein-positive oligodendrocytes in vitro and promotes remyelination in vivo. Also displays antimuscarinic properties. Clinically-used antihistamine.

Product Specifications

Molecular Weight

459.97

Formula

C21H26ClNO.C4H4O4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy]ethyl]-1-methyl-2-pyrrolidine fumarate

CAS Number

14976-57-9

PubChem ID

5281069

InChI Key

PMGQWSIVQFOFOQ-YKVZVUFRSA-N

SMILES

[H]OC(=O)\C=C\C(=O)O[H].CN1CCC[C@@H]1CCO[C@](C)(C1=CC=CC=C1)C1=CC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 9.2 20

Preparing Stock Solutions for Clemastine fumarate

The following data is based on the product molecular weight 459.97

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 10.87 mL 54.35 mL 108.70 mL
1 mM 2.17 mL 10.87 mL 21.74 mL
2 mM 1.09 mL 5.44 mL 10.87 mL
10 mM 0.22 mL 1.09 mL 2.17 mL

Calculators

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Reconstitution Calculator

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Product Documents for Clemastine fumarate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Clemastine fumarate

For research use only

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