CITFA
Tocris Bioscience, part of Bio-Techne | Catalog # 7811
Potent G protein-coupled estrogen receptor (GPER) agonist
Key Product Details
Description
Potent G protein-coupled estrogen receptor (GPER) agonist
Product Description
CITFA is a potent GPER agonist (EC50 = 38.7 nM). It significantly increases axonal and dendritic growth in rat embryonic (E18) hippocampal neurons.Licensing Information
Sold under licence from Saint Louis University.Product Specifications
Molecular Weight
381.56
Formula
C25H35NO2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-[2-Cyclohexyl-4-(1-methylethyl)phenyl]-5-(tetrahydro-2H-pyran-2-yl)-2-furanmethanamine
CAS Number
2379989-52-1
PubChem ID
153360510
InChI Key
GYTVCHRGONLGMD-UHFFFAOYSA-N
SMILES
CC(C)C(C=C1C2CCCCC2)=CC=C1NCC3=CC=C(C4OCCCC4)O3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 19.08 | 50 | |
| Ethanol | 3.82 | 10 |
Preparing Stock Solutions
for CITFA
The following data is based on the product molecular weight 381.56
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 5.24 mL | 26.21 mL | 52.42 mL |
| 2.5 mM | 1.05 mL | 5.24 mL | 10.48 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.24 mL |
| 25 mM | 0.10 mL | 0.52 mL | 1.05 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- DeLeon Novel GPER agonist, CITFA, increases neurite growth in rat embryonic (E18) hippocampal neurons. ACS Chem.Neurosci. 2022 PMID: 35353510
Product Specific Notices for CITFA
For research use only
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