CIQ
Tocris Bioscience, part of Bio-Techne | Catalog # 4105
Potentiator of NMDA receptors containing GluN2C/GluN2D
Key Product Details
Description
Potentiator of NMDA receptors containing GluN2C/GluN2D
Product Description
CIQ is a subunit-selective potentiator of NMDA receptors containing the GluN2C (formally NR2C) or GluN2D (formally NR2D) subunit. Increases channel opening efficiency and enhances NMDA receptor responses.Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.
Product Specifications
Molecular Weight
467.94
Formula
C26H26ClNO5
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
(3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone
CAS Number
486427-17-2
PubChem ID
4231127
InChI Key
VYMILMYEENZHAR-UHFFFAOYSA-N
SMILES
O=C(C3=CC(Cl)=CC=C3)N2C(COC4=CC=C(OC)C=C4)C1=CC(OC)=C(OC)C=C1CC2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 46.79 | 100 |
Preparing Stock Solutions
for CIQ
The following data is based on the product molecular weight 467.94
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.14 mL | 10.69 mL | 21.37 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.27 mL |
| 10 mM | 0.21 mL | 1.07 mL | 2.14 mL |
| 50 mM | 0.04 mL | 0.21 mL | 0.43 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Mullasseril A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. Nat.Commun. 2010 PMID: 20975674
Product Specific Notices for CIQ
For research use only
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