Cinalukast

Name: Cinalukast
Brand: Tocris Bioscience
SKU: 2025

Tocris Bioscience, part of Bio-Techne | Catalog # 2025

Citations (4104)

COA / SDS

Potent, selective CysLT1 (LTD4) antagonist; orally active

Discontinued Product

2025 has been discontinued. View all Leukotriene and Related Receptor Antagonists products.

Key Product Details

Description:	Potent, selective CysLT₁(LTD₄) antagonist; orally active
Alternative Names:	Ro 24-5913
Chemical Name:	4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
Purity:	≥98% (HPLC)
Molecular Weight:	412.55

View Full Technical Details for Cinalukast

Technical Data
Citations

Biological Activity for Cinalukast

Potent, selective CysLT₁ (LTD₄) leukotriene receptor antagonist (IC₅₀ = 6.4 nM). Inhibits LTD₄-induced bronchoconstriction in guinea pigs when administered intravenously, orally or by aerosol.

Technical Data for Cinalukast

M. Wt	412.55
Formula	C₂₃H₂₈N₂O₃S
Storage	Desiccate at -20°C
Purity	≥98% (HPLC)
CAS Number	128312-51-6
PubChem ID	6436135
InChi Key	BZMKNPGKXJAIDV-VAWYXSNFSA-N
Smiles	CCC(CC)(CC(=O)NC1=CC(\C=C\C2=NC(=CS2)C2CCC2)=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Cinalukast

References are publications that support the biological activity of the product.

O'Donnell Pharmacologic actions of Ro 24-5913, a novel antagonist of leukotriene D₄. J.Pharmacol.Exp.Ther. 1991 PMID: 1658310
O'Donnell Ro 24-5913: a potent, specific, orally active LTD4 antagonist. Ann.N.Y.Acad.Sci. 1991 PMID: 1659286

Cinalukast

Tocris Bioscience, part of Bio-Techne | Catalog # 2025

Key Product Details

Biological Activity for Cinalukast

Technical Data for Cinalukast

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Cinalukast

Product Documents for Cinalukast

COA

Certificate of Analysis

SDS

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