Cilostamide

Tocris Bioscience, part of Bio-Techne | Catalog # 0915

PDE3 inhibitor
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Key Product Details

Description

PDE3 inhibitor

Alternative Names

OCP 3689

View all Phosphodiesterase Inhibitors »

Product Description

Cilostamide is a selective inhibitor of type III phosphodiesterase (PDE3). Displays moderate selectivity for PDE3A isozyme vs. PDE3B (IC50 values are 0.027 and 0.050 μM for PDE3A and PDE3B respectively). Inhibits ADP-induced platelet aggregation (IC50 = 16.8 μM); antithrombotic.

Product Specifications

Molecular Weight

342.44

Formula

C20H26N2O3

Storage

Store at RT

Purity

≥97% (HPLC)

Chemical Name

N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide

CAS Number

68550-75-4

PubChem ID

2753

InChI Key

UIAYVIIHMORPSJ-UHFFFAOYSA-N

SMILES

CN(C1CCCCC1)C(=O)CCCOC1=CC=C2NC(=O)C=CC2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 6.85 20 with gentle warming

Preparing Stock Solutions for Cilostamide

The following data is based on the product molecular weight 342.44

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 14.60 mL 73.01 mL 146.01 mL
1 mM 2.92 mL 14.60 mL 29.20 mL
2 mM 1.46 mL 7.30 mL 14.60 mL
10 mM 0.29 mL 1.46 mL 2.92 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Cilostamide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cilostamide

For research use only

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