CID 755673
Tocris Bioscience, part of Bio-Techne | Catalog # 3327
Selective protein kinase D inhibitor
Key Product Details
Description
Selective protein kinase D inhibitor
Product Description
CID 755673 is a selective protein kinase D (PKD) inhibitor (IC50 values are 0.182, 0.280, 0.227, >10, 15.3, 20.3, 40.5 and >50 μM at PKD1, PKD2, PKD3, PKC, CAK, PLK1, CAMKIIα and Akt respectively). Blocks PKD-mediated protein transport and inhibits prostate cancer cell proliferation, migration and invasion in vitro.Product Specifications
Molecular Weight
217.22
Formula
C12H11NO3
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one
CAS Number
521937-07-5
PubChem ID
755673
InChI Key
AACFPJSJOWQNBN-UHFFFAOYSA-N
SMILES
OC1=CC2=C(OC3=C2CCCNC3=O)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 21.72 | 100 |
Preparing Stock Solutions
for CID 755673
The following data is based on the product molecular weight 217.22
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.60 mL | 23.02 mL | 46.04 mL |
| 5 mM | 0.92 mL | 4.60 mL | 9.21 mL |
| 10 mM | 0.46 mL | 2.30 mL | 4.60 mL |
| 50 mM | 0.09 mL | 0.46 mL | 0.92 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Sharlow Potent and selective disruption of protein kinase D functionality by benzoxoloazepinolone. J.Biol.Chem. 2008 PMID: 18829454
Product Specific Notices for CID 755673
For research use only
Loading...
Loading...
Loading...