Chemerin-9, Human
Tocris Bioscience, part of Bio-Techne | Catalog # 7116
Potent CMKLR1 agonist; c-terminal peptide of full length human chemerin
Key Product Details
Description
Potent CMKLR1 agonist; c-terminal peptide of full length human chemerin
Product Description
Chemerin-9, Human is a potent chemokine-like receptor 1 (CMKLR1; also known as chemerin receptor 23, ChemR23) agonist (EC50 = 7.1 nM at CMKLR expressed in CHO cells). Corresponds to C-terminal of full length human Chemerin, amino acids 149 - 157. Activates Gi/o signaling pathways in vitro; inhibits cAMP production and promotes phospholipase C production and Ca2+ mobilization.Product Specifications
Molecular Weight
1063.18
Formula
C54H66N10O13
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
676367-27-4
PubChem ID
11332190
InChI Key
QLVGSBXIQFERFK-NBBYSTNSSA-N
SMILES
O=C(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=C(C=C5)O)N
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- De Henau Signaling properties of chemerin receptors CMKLR1, GPR1 and CCRL2. PLoS One. 2016 PMID: 27716822
- Wittamer The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency. J.Med.Chem. 2004 PMID: 14701797
Product Specific Notices for Chemerin-9, Human
For research use only
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