CGP 37157

Tocris Bioscience, part of Bio-Techne | Catalog # 1114

Antagonist of mitochondrial Na+/Ca2+ exchange
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Key Product Details

Description

Antagonist of mitochondrial Na+/Ca2+ exchange

View all Na+/Ca2+ Exchanger Inhibitors »

Product Description

CGP 37157 is a selective antagonist of the mitochondrial Na+/Ca2+ exchanger (NCX; IC50 = 0.4 μM).

Product Specifications

Molecular Weight

324.22

Formula

C15H11Cl2NOS

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one

CAS Number

75450-34-9

PubChem ID

2688

InChI Key

KQEPIRKXSUIUTH-UHFFFAOYSA-N

SMILES

ClC1=CC=C2NC(=O)CSC(C3=CC=CC=C3Cl)C2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 100

Preparing Stock Solutions for CGP 37157

The following data is based on the product molecular weight 324.22

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.08 mL 15.42 mL 30.84 mL
5 mM 0.62 mL 3.08 mL 6.17 mL
10 mM 0.31 mL 1.54 mL 3.08 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for CGP 37157

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CGP 37157

For research use only

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