CGP 36216 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 3219
GABAB antagonist; displays activity at presynaptic receptors
Key Product Details
Description
GABAB antagonist; displays activity at presynaptic receptors
Product Description
CGP 36216 hydrochloride is a selective GABAB antagonist. Displays activity at presynaptic receptors; ineffective at GABAB postsynaptic receptors.Product Specifications
Molecular Weight
187.60
Formula
C5H14NO2P.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
(3-Aminopropyl)ethylphosphinic acid hydrochloride
CAS Number
1781834-71-6
PubChem ID
90488815
InChI Key
CFQFXUJBWMPODB-UHFFFAOYSA-N
SMILES
O=P(CC)(CCCN)O.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 18.76 | 100 | |
| DMSO | 18.76 | 100 |
Preparing Stock Solutions
for CGP 36216 hydrochloride
The following data is based on the product molecular weight 187.60
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.33 mL | 26.65 mL | 53.30 mL |
| 5 mM | 1.07 mL | 5.33 mL | 10.66 mL |
| 10 mM | 0.53 mL | 2.67 mL | 5.33 mL |
| 50 mM | 0.11 mL | 0.53 mL | 1.07 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Froestl Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists. J.Med.Chem. 1995 PMID: 7650685
- Ong CGP 36216 is a selective antagonist at GABAB presynaptic receptors in rat brain. Eur.J.Pharmacol. 2001 PMID: 11274998
Product Specific Notices for CGP 36216 hydrochloride
For research use only
Loading...
Loading...