CASIN

Tocris Bioscience, part of Bio-Techne | Catalog # 5050

Cdc42 inhibitor
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Key Product Details

Description

Cdc42 inhibitor

View all Rho GTPase Inhibitors »

Product Description

CASIN is a Cdc42 GTPase inhibitor (IC50 = 2 μM). Reduces active levels of Cdc42 in aged hematopoietic stem cells (HSCs) to that in young HSCs. Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo. Increases histone H4K16 acetylation in aged HSCs.

Product Specifications

Molecular Weight

306.40

Formula

C20H22N2O

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol

CAS Number

425399-05-9

PubChem ID

2882155

InChI Key

RXIUMAOXORBRCY-UHFFFAOYSA-N

SMILES

OCCNC1C2=C(C(C=C(C4=CC=CC=C4)C=C3)=C3N2)CCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.64 100
Ethanol 15.32 50

Preparing Stock Solutions for CASIN

The following data is based on the product molecular weight 306.40

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.26 mL 16.32 mL 32.64 mL
5 mM 0.65 mL 3.26 mL 6.53 mL
10 mM 0.33 mL 1.63 mL 3.26 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for CASIN

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CASIN

For research use only

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