Carbazeran citrate

Name: Carbazeran citrate
Brand: Tocris Bioscience
SKU: 4420

Tocris Bioscience, part of Bio-Techne | Catalog # 4420

COA / SDS

Aldehyde oxidase substrate; PDE inhibitor

Discontinued Product

4420 has been discontinued. View all Other Oxidase/Oxygenase Compounds products.

Key Product Details

Description:	Aldehyde oxidase substrate; PDE inhibitor
Chemical Name:	Ethyl 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl carbamate citrate
Purity:	≥98% (HPLC)
Molecular Weight:	552.53

View Full Technical Details for Carbazeran citrate

Technical Data
Citations

Biological Activity for Carbazeran citrate

Carbazeran citrate is an aldehyde oxidase (AO) substrate. Exhibits activities as a phosphodiesterase inhibitor; produces concentration-dependent positive inotropic responses in isolated right atria.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data for Carbazeran citrate

M. Wt	552.53
Formula	C₁₈H₂₄N₄O₄.C₆H₈O₇
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	153473-94-0
PubChem ID	90488940
InChi Key	QKMRPDVEKBYWPF-UHFFFAOYSA-N
Smiles	O=C(NCC)OC(CC3)CCN3C2=NN=CC1=CC(OC)=C(OC)C=C12.OC(CC(C(O)=O)(O)CC(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Carbazeran citrate

References are publications that support the biological activity of the product.

Shahid and Rodger Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition. Br.J.Pharmacol. 1989 PMID: 2478244
Hutzler Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes. Drug Metab.Dispos. 2011 PMID: 22031625