Capsazepine

Tocris Bioscience, part of Bio-Techne | Catalog # 0464

TRPV antagonist; also activator of ENaCδ
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Key Product Details

Description

TRPV antagonist; also activator of ENaCδ

View all TRPV Antagonists »

Product Description

Capsazepine is a selective vanilloid receptor antagonist (Ki = 3.2 μM). Inhibits carrageenan inflammation-induced hyperalgesic responses in the rat. Also activates amiloride-sensitive epithelial Na+ channel ENaCδ.

Product Specifications

Molecular Weight

376.90

Formula

C19H21ClN2O2S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide

CAS Number

138977-28-3

PubChem ID

2733484

InChI Key

DRCMAZOSEIMCHM-UHFFFAOYSA-N

SMILES

OC1=C(O)C=C2CN(CCCC2=C1)C(=S)NCCC1=CC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 37.69 100
Ethanol 9.42 25

Preparing Stock Solutions for Capsazepine

The following data is based on the product molecular weight 376.90

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.65 mL 13.27 mL 26.53 mL
5 mM 0.53 mL 2.65 mL 5.31 mL
10 mM 0.27 mL 1.33 mL 2.65 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

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Product Documents for Capsazepine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Capsazepine

For research use only

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