Cannabigerol
Tocris Bioscience, part of Bio-Techne | Catalog # 3021
Cannabinoid receptor partial agonist
Key Product Details
Description
Cannabinoid receptor partial agonist
Product Description
Cannabigerol is a partial agonist of CB2 and CB1 receptors (Ki values are 337 and 440 nM respectively). Also exhibits α2-adrenoceptor agonist activity (EC50 = 0.2 nM in mouse brain membranes).Product Specifications
Molecular Weight
316.48
Formula
C21H32O2
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
2-[(2E)-3,7-Dimethyl-2,6-octadienyl)-5-pentyl-1,3-benzenediol
CAS Number
25654-31-3
PubChem ID
5315659
InChI Key
QXACEHWTBCFNSA-SFQUDFHCSA-N
SMILES
OC(C=C(CCCCC)C=C1O)=C1C/C=C(C)/CC/C=C(C)\C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.65 | 100 | |
| Ethanol | 31.65 | 100 |
Preparing Stock Solutions
for Cannabigerol
The following data is based on the product molecular weight 316.48
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.16 mL | 15.80 mL | 31.60 mL |
| 5 mM | 0.63 mL | 3.16 mL | 6.32 mL |
| 10 mM | 0.32 mL | 1.58 mL | 3.16 mL |
| 50 mM | 0.06 mL | 0.32 mL | 0.63 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Cascio Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. Br.J.Pharmacol. 2010 PMID: 20002104
- Gauson Cannabigerol behaves as a partial agonist at both CB1 and CB2 receptors. Symposium on the Cannabinoids
- Pertwee The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. Br.J.Pharmacol. PMID: 17828291
Product Specific Notices for Cannabigerol
For research use only
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