Caerulein
Tocris Bioscience, part of Bio-Techne | Catalog # 6264
CCK agonist
Product Description
Caerulein is a CCK agonist. Stimulates biosynthesis of pancreatic enzymes in AR4-2J pancreatic cells in vitro. Induces acute pancreatitis in mice. Also enhances proteasome activity in Gdeg mice.Product Specifications
Molecular Weight
1352.40
Formula
C58H73N13O21S2
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
17650-98-5
PubChem ID
16132921
InChI Key
YRALAIOMGQZKOW-UHFFFAOYSA-N
SMILES
CC(C(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5)O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Furuyama Proteasome activity is required for the initiation of precancerous pancreatic lesions. Sci.Rep. 2016 PMID: 27244456
- Pradel Caerulein and gastrin(2-17 ds) regulate differently synthesis of secretory enzymes, mRNA levels and cell proliferation in pancreatic acinar cells (AR4-2J). Biochem.J. 1993 PMID: 7679894
- Murakami Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma. Oncogene 2017 PMID: 27546622
Product Specific Notices for Caerulein
For research use only
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