BRL 50481
Tocris Bioscience, part of Bio-Techne | Catalog # 2237
Selective PDE7 inhibitor
Product Description
BRL 50481 is a selective, substrate-competitive inhibitor of phosphodiesterase (PDE) 7 (Ki = 180 nM). Displays > 200-fold selectivity over PDE1B, PDE1C, PDE2, PDE3, PDE4A4 and PDE5.Licensing Information
Sold with the permission of GlaxoSmithKlineProduct Specifications
Molecular Weight
244.26
Formula
C9H12N2O4S
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
N,N,2-Trimethyl-5-nitro-benzenesulfonamide
CAS Number
433695-36-4
PubChem ID
2921148
InChI Key
IFIUFCJFLGCQPH-UHFFFAOYSA-N
SMILES
CN(C)S(=O)(=O)C1=C(C)C=CC(=C1)[N+]([O-])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.43 | 100 | |
| Ethanol | 24.43 | 100 |
Preparing Stock Solutions
for BRL 50481
The following data is based on the product molecular weight 244.26
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.09 mL | 20.47 mL | 40.94 mL |
| 5 mM | 0.82 mL | 4.09 mL | 8.19 mL |
| 10 mM | 0.41 mL | 2.05 mL | 4.09 mL |
| 50 mM | 0.08 mL | 0.41 mL | 0.82 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for BRL 50481
For research use only
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