BRD 7389

Name: BRD 7389
Brand: Tocris Bioscience
SKU: 4037

Tocris Bioscience, part of Bio-Techne | Catalog # 4037

Citations (8)

COA / SDS

Ribosomal S6 kinase inhibitor

Discontinued Product

4037 has been discontinued. View all RSK Inhibitors products.

Key Product Details

Description:	Ribosomal S6 kinase inhibitor
Chemical Name:	1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione
Purity:	≥97% (HPLC)
Molecular Weight:	366.41

View Full Technical Details for BRD 7389

Technical Data
Citations

Biological Activity for BRD 7389

BRD 7389 is a ribosomal S6 kinase (RSK) inhibitor (IC₅₀ values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in terminally differentiated pancreatic α-cells.

Technical Data for BRD 7389

M. Wt	366.41
Formula	C₂₄H₁₈N₂O₂
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	376382-11-5
PubChem ID	1080352
InChi Key	XASCINRGTHLHGM-UHFFFAOYSA-N
Smiles	O=C(C3=C2C(N4)=CC=C3)C1=CC=CC=C1C2=C(NCCC5=CC=CC=C5)C4=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for BRD 7389

References are publications that support the biological activity of the product.

Fomina-Yadlin Small molecule inducers of Ins expression in pancreatic alpha cells. Proc.Natl.Acad.Sci.U.S.A. 2010 PMID: 20696901

BRD 7389

Tocris Bioscience, part of Bio-Techne | Catalog # 4037

Key Product Details

Biological Activity for BRD 7389

Technical Data for BRD 7389

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for BRD 7389

Product Documents for BRD 7389

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

保持关注