BQ-3020
Tocris Bioscience, part of Bio-Techne | Catalog # 1189
Selective ETB agonist
Product Description
BQ-3020 is a highly potent and selective ETB endothelin receptor agonist (Ki values are 0.18 and 970 nM at human ETB and ETA receptors respectively).Product Specifications
Molecular Weight
2006.35
Formula
C96H140N20O25S
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
143113-45-5
PubChem ID
16135850
InChI Key
AYJUXFCWNAVJLN-FHOIYVHLSA-N
SMILES
CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 0.5mg/ml in sodium bicarbonate (0.03M) |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Sakamoto Distinct subdomains of human endothelin receptors determine their selectivity to endothelinA-selective antagonist and endothelinB-selective agonists. J.Biol.Chem. 1993 PMID: 8473300
- Ihara [3H]-BQ-123, a highly specific and reversible radioligand for the endothelin ETA receptor subtype. Eur.J.Pharmacol. 1995 PMID: 7768260
- Reynolds Pharmacological differences between rat and human endothelin B receptors. Biochem.Biophys.Res.Commun. 1995 PMID: 7733918
- Ekelund Effects of selective ETB-receptor stimulation on arterial, venous and capillary functions in cat skeletal muscle. Br.J.Pharmacol. 1994 PMID: 7921617
Product Specific Notices for BQ-3020
For research use only
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