BD 1063 dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0883

Selective σ1 ligand, putative antagonist
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Key Product Details

Description

Selective σ1 ligand, putative antagonist

View all Sigma1 Receptor Ligands »

Product Description

BD 1063 dihydrochloride is a σ1 receptor antagonist, approximately 50-fold selective over σ2 sites and ≥100-fold selective over opioid, PCP, muscarinic, dopamine, α1, α2, β adrenoceptor, 5-HT1 and 5-HT2 receptors. Prevents hyperlocomotion following cocaine administration in mice.

Product Specifications

Molecular Weight

346.13

Formula

C13H18Cl2N2.2HCl

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine dihydrochloride

CAS Number

206996-13-6

PubChem ID

11617161

InChI Key

NXFDBTLQOARIMH-UHFFFAOYSA-N

SMILES

Cl.Cl.CN1CCN(CCC2=CC=C(Cl)C(Cl)=C2)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 34.61 100

Preparing Stock Solutions for BD 1063 dihydrochloride

The following data is based on the product molecular weight 346.13

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.89 mL 14.45 mL 28.89 mL
5 mM 0.58 mL 2.89 mL 5.78 mL
10 mM 0.29 mL 1.44 mL 2.89 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for BD 1063 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BD 1063 dihydrochloride

For research use only

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