Product Description
BCH is an inhibitor of L-type amino acid transporter LAT1. Suppresses growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines.Product Specifications
Molecular Weight
155.20
Formula
C8H13NO2
Storage
Store at RT
Chemical Name
2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid
CAS Number
20448-79-7
PubChem ID
115288
InChI Key
MPUVBVXDFRDIPT-UHFFFAOYSA-N
SMILES
NC1(C(O)=O)CC2CCC1C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.52 | 100 |
Preparing Stock Solutions
for BCH
The following data is based on the product molecular weight 155.20
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.44 mL | 32.22 mL | 64.43 mL |
| 5 mM | 1.29 mL | 6.44 mL | 12.89 mL |
| 10 mM | 0.64 mL | 3.22 mL | 6.44 mL |
| 50 mM | 0.13 mL | 0.64 mL | 1.29 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Lin L-type amino acid transporter-1 overexpression and melp. sensitivity in Barrett's adenocarcinoma. Neoplasia 2004 PMID: 15068672
- Fraga L-type amino acid transporters in two intestinal epithelial cell lines function as exchangers with neutral amino acids. J.Nutr. 2002 PMID: 11925469
- Kim BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. Biol.Pharm.Bull. 2008 PMID: 18520037
Product Specific Notices for BCH
For research use only
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