B-HT 933 dihydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 2758
Selective α2 agonist
Key Product Details
Description
Selective α2 agonist
Alternative Names
Azepexole
Product Description
B-HT 933 dihydrochloride is a selective α2-adrenoceptor agonist. Exhibits greater than 300-fold selectivity for the α2-adrenoceptor over the α1-adrenoceptor.Product Specifications
Molecular Weight
254.16
Formula
C9H15N3O.2HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride
CAS Number
36067-72-8
PubChem ID
169743
InChI Key
HBLPYIOKPJVFQW-UHFFFAOYSA-N
SMILES
CCN1CCC(OC(N)=N2)=C2CC1.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 25.42 | 100 | |
| DMSO | 12.71 | 50 |
Preparing Stock Solutions
for B-HT 933 dihydrochloride
The following data is based on the product molecular weight 254.16
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.93 mL | 19.67 mL | 39.35 mL |
| 5 mM | 0.79 mL | 3.93 mL | 7.87 mL |
| 10 mM | 0.39 mL | 1.97 mL | 3.93 mL |
| 50 mM | 0.08 mL | 0.39 mL | 0.79 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Parkinson and Hughes The mechanism of action of α2-adrenoceptors in human isolated subcutaneous resistance arteries. Br.J.Pharmacol. 1995 PMID: 8564206
- Kobinger and Pichler Pharmacological characterization of B-HT 933 (2-amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazolo-[5,4-d]-azepindihydrochloride) as a hypotensive agent of the "clonidine-type". Naunyn-Schmied.Arch.Pharmacol. 1977 PMID: 22821
- Bill The thermogenic actions of α2-adrenoceptor agonists in reserpinized mice are mediated via a central postsynaptic α2-adrenoceptor mechanism. Br.J.Pharmacol. 1989 PMID: 2564288
Product Specific Notices for B-HT 933 dihydrochloride
For research use only
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