AZM 475271

Tocris Bioscience, part of Bio-Techne | Catalog # 3963

Src tyrosine kinase inhibitor
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Key Product Details

Description

Src tyrosine kinase inhibitor

View all Src Family Kinase Inhibitors »

Product Description

AZM 475271 is a src tyrosine kinase inhibitor. Reduces tumor size, vascularity and metastasis, and increases apoptosis in human pancreatic cells grown in nude mice. Also exhibits antiangiogenic activity in vitro and in vivo. Sensitizes tumor cells to the cytotoxic effects of gemcitabine (Cat. No. 3259).

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Product Specifications

Molecular Weight

442.94

Formula

C23H27ClN4O3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-(2-Chloro-5-methoxyphenyl)-6-methoxy

CAS Number

476159-98-5

PubChem ID

5330175

InChI Key

WPOXAFXHRJYEIC-UHFFFAOYSA-N

SMILES

ClC1=CC=C(OC)C=C1NC3=NC=NC2=CC(OCC4CCN(C)CC4)=C(OC)C=C23

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 44.29 100

Preparing Stock Solutions for AZM 475271

The following data is based on the product molecular weight 442.94

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.26 mL 11.29 mL 22.58 mL
5 mM 0.45 mL 2.26 mL 4.52 mL
10 mM 0.23 mL 1.13 mL 2.26 mL
50 mM 0.05 mL 0.23 mL 0.45 mL

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Product Documents for AZM 475271

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AZM 475271

For research use only

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