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Atosiban

Tocris Bioscience, part of Bio-Techne | Catalog # 6332

Potent oxytocin receptor antagonist
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6332/10

Key Product Details

Description

Potent oxytocin receptor antagonist

Product Description

Atosiban is a potent oxytocin receptor (OTR) antagonist. Inhibits oxytocin-induced increase in Ca2+ concentration in myometrial cells in vitro (IC50 = 5 nM) Activates NF-κB and MAPK pathways in human amnion via Gαi signaling, resulting in pro-inflammatory effects. Inhibits oxytocin-induced uterine contractions in vivo and in vitro. Effective in a rat preterm labor model.

Product Specifications

Molecular Weight

994.19

Formula

C43H67N11O12S2

Storage

Store at -20°C

Purity

≥98% (HPLC)

CAS Number

90779-69-4

PubChem ID

5311010

InChI Key

VWXRQYYUEIYXCZ-OBIMUBPZSA-N

SMILES

[H][C@@]1([C@H](O)C)NC(C([C@H](CC)C)NC([C@H](NC(CCSSC[C@@H](C(N2CCC[C@H]2C(N[C@H](C(NCC(N)=O)=O)CCCN)=O)=O)NC([C@@H](NC1=O)CC(N)=O)=O)=O)CC3=CC=C(C=C3)OCC)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 50mg/ml in water

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Product Documents for Atosiban

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Atosiban

For research use only

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