AR 420626
Tocris Bioscience, part of Bio-Techne | Catalog # 6163
FFA3 agonist
Product Description
AR 420626 is a FFA3 agonist (pEC50 = 5.74). Inhibits nicotine and serotonin induced changes in motility of isolated muscle strips from rat colon. Also suppresses serotonin-induced fecal output in rats.Product Specifications
Molecular Weight
417.29
Formula
C21H18Cl2N2O3
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide
CAS Number
1798310-55-0
PubChem ID
11509934
InChI Key
BYLWSJCOCFUZDH-UHFFFAOYSA-N
SMILES
CC1=C(C(NC2=C(C=CC(Cl)=C2)Cl)=O)C(C3=C(N1)CCCC3=O)C4=CC=CO4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.86 | 50 |
Preparing Stock Solutions
for AR 420626
The following data is based on the product molecular weight 417.29
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.79 mL | 23.96 mL | 47.93 mL |
| 2.5 mM | 0.96 mL | 4.79 mL | 9.59 mL |
| 5 mM | 0.48 mL | 2.40 mL | 4.79 mL |
| 25 mM | 0.10 mL | 0.48 mL | 0.96 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kaji Free fatty acid receptor 3 activation suppresses neurogenic motility in rat proximal colon. Neurogastroenterol.Motil. 2017 PMID: 28714277
- Hudson Complex pharmacology of novel allosteric free fatty acid 3 receptor ligands. Mol Pharmacol. 2014 PMID: 24870406
Product Specific Notices for AR 420626
For research use only
Loading...
Loading...