Antalarmin hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2778

CRF1 antagonist
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Key Product Details

Description

CRF1 antagonist

View all CRF1 Receptor Antagonists »

Product Description

Antalarmin hydrochloride is a non-peptide corticotropin-releasing hormone receptor 1 (CRF1) antagonist (Ki = 1 nM). Suppresses CRF-induced ACTH secretion. Blocks CRF- and novelty-induced anxiety-like behavior in animal models of anxiety.

Product Specifications

Molecular Weight

415.01

Formula

C24H34N4.HCl

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride

CAS Number

220953-69-5

PubChem ID

16078945

InChI Key

CGDGXEDXEXACKQ-UHFFFAOYSA-N

SMILES

CC1=C(C)N(C3=C(C)C=C(C)C=C3C)C2=C1C(N(CC)CCCC)=NC(C)=N2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.5 100
Ethanol 41.5 100

Preparing Stock Solutions for Antalarmin hydrochloride

The following data is based on the product molecular weight 415.01

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.41 mL 12.05 mL 24.10 mL
5 mM 0.48 mL 2.41 mL 4.82 mL
10 mM 0.24 mL 1.20 mL 2.41 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Calculators

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Product Documents for Antalarmin hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Antalarmin hydrochloride

For research use only

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