AMTB hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 3989
TRPM8 blocker
Product Description
AMTB hydrochloride is a TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in a rat model (pIC50 = 6.23).Product Specifications
Molecular Weight
430.99
Formula
C23H26N2O2S.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride
CAS Number
926023-82-7
PubChem ID
16095383
InChI Key
UDXGBANGPYONOK-UHFFFAOYSA-N
SMILES
O=C(N(CC2=CC=CS2)CCCN)C1=C(OCC3=CC(C)=CC=C3)C=CC=C1.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 43.1 | 100 | |
| DMSO | 43.1 | 100 |
Preparing Stock Solutions
for AMTB hydrochloride
The following data is based on the product molecular weight 430.99
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.32 mL | 11.60 mL | 23.20 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.64 mL |
| 10 mM | 0.23 mL | 1.16 mL | 2.32 mL |
| 50 mM | 0.05 mL | 0.23 mL | 0.46 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Lashinger AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome. Am.J.Physiol.Renal Physiol. 2008 PMID: 18562636
Product Specific Notices for AMTB hydrochloride
For research use only
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