AM 630

Tocris Bioscience, part of Bio-Techne | Catalog # 1120

Selective CB2 inverse agonist
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Key Product Details

Description

Selective CB2 inverse agonist

View all Cannabinoid R2/CB2 Inverse Agonists »

Product Description

AM 630 is a CB2 inverse agonist (Ki = 31.2 nM) that displays 165-fold selectivity over CB1 receptors. Behaves as a weak partial/inverse agonist at CB1 receptors.

Product Specifications

Molecular Weight

504.37

Formula

C23H25IN2O3

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

6-Iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)methanone

CAS Number

164178-33-0

PubChem ID

4302963

InChI Key

JHOTYHDSLIUKCJ-UHFFFAOYSA-N

SMILES

COC1=CC=C(C=C1)C(=O)C1=C(C)N(CCN2CCOCC2)C2=CC(I)=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 50.44 100

Preparing Stock Solutions for AM 630

The following data is based on the product molecular weight 504.37

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.98 mL 9.91 mL 19.83 mL
5 mM 0.40 mL 1.98 mL 3.97 mL
10 mM 0.20 mL 0.99 mL 1.98 mL
50 mM 0.04 mL 0.20 mL 0.40 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for AM 630

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AM 630

For research use only

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