Alfuzosin hydrochloride

Name: Alfuzosin hydrochloride
Brand: Tocris Bioscience
SKU: 3305
Rating: 4 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3305

(1)

COA / SDS

Uroselective α1 antagonist

Discontinued Product

3305 has been discontinued. View all Adrenergic alpha-1 Receptor Antagonists products.

Key Product Details

Description:	Uroselective α₁ antagonist
Chemical Name:	N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	425.91

View Full Technical Details for Alfuzosin hydrochloride

Technical Data
Citations / Reviews (1)

Biological Activity for Alfuzosin hydrochloride

Alfuzosin hydrochloride is a functionally uro-selective α₁ adrenoceptor antagonist that does not discriminate between α₁ subtypes. Inhibits increases in intraurethral pressure caused by phenylephrine-induced contraction by 81% with minor cardiovascular effects. Also relaxes corpus cavernosum tissue (pIC₅₀ = 7.64) in vitro.

Technical Data for Alfuzosin hydrochloride

M. Wt	425.91
Formula	C₁₉H₂₇N₅O₄.HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	81403-68-1
PubChem ID	71764
InChi Key	YTNKWDJILNVLGX-UHFFFAOYSA-N
Smiles	NC2=NC(N(C)CCCNC(C3CCCO3)=O)=NC1=CC(OC)=C(OC)C=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Alfuzosin hydrochloride

References are publications that support the biological activity of the product.

Lee Alfuzosin hydrocholride for the treatment of benign prostatic hyperplasia. Am.J.Health Syst.Pharm. 2003 PMID: 12892027
Yamaguchi Effects of different alpha-1 adrenoceptor blockers on proximal urethral function using in vivo isovolumetric pressure changes. J.Smooth Muscle Res. 2005 PMID: 16428864
Palea and Barras Comparison of the relaxant effects of alfuzosin, phentol. and silde. on rabbit isolated corpus cavernosum. BJU Int. 2003 PMID: 12780851

Alfuzosin hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 3305

Key Product Details

Biological Activity for Alfuzosin hydrochloride

Technical Data for Alfuzosin hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Alfuzosin hydrochloride

Product Documents for Alfuzosin hydrochloride

COA

Certificate of Analysis

SDS

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