AG 205

Tocris Bioscience, part of Bio-Techne | Catalog # 6242

Progesterone receptor membrane component 1 (Pgrmc1) ligand
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Key Product Details

Description

Progesterone receptor membrane component 1 (Pgrmc1) ligand

View all Other Nuclear Receptor Compounds »

Product Description

AG 205 is a progesterone receptor membrane component 1 (Pgrmc1) ligand. Inhibits cell cycle progression and cell viability in cancer cell lines. Inhibits progesterone induced cytosolic Ca2+ increases in GnRH neurons in vitro.

Product Specifications

Molecular Weight

454.98

Formula

C22H23ClN6OS

Storage

Store at +4°C

Purity

≥97% (HPLC)

Chemical Name

cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone

CAS Number

442656-02-2

PubChem ID

4240652

InChI Key

GJNBAISSZRNGTM-UHFFFAOYSA-N

SMILES

[H][C@@]12CCN(C)C[C@]1([H])C1=CC(C)=CC=C1N2C(=O)CSC1=NN=NN1C1=CC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 22.75 50

Preparing Stock Solutions for AG 205

The following data is based on the product molecular weight 454.98

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.40 mL 21.98 mL 43.96 mL
2.5 mM 0.88 mL 4.40 mL 8.79 mL
5 mM 0.44 mL 2.20 mL 4.40 mL
25 mM 0.09 mL 0.44 mL 0.88 mL

Calculators

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Product Documents for AG 205

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AG 205

For research use only

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