AEBSF
Tocris Bioscience, part of Bio-Techne | Catalog # 5175
Broad spectrum, irreversible inhibitor of serine proteases
Key Product Details
Description
Broad spectrum, irreversible inhibitor of serine proteases
Product Description
AEBSF is a broad spectrum, irreversible inhibitor of serine proteases. Also inhibits NADPH oxidase activation in vitro. Attenuates airway inflammation in a mouse model of airway allergy.Product Specifications
Molecular Weight
239.69
Formula
C8H10FNO2S.HCl
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
CAS Number
30827-99-7
PubChem ID
186136
InChI Key
WRDABNWSWOHGMS-UHFFFAOYSA-N
SMILES
NCCC1=CC=C(S(=O)(F)=O)C=C1.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 23.97 | 100 | |
| DMSO | 23.97 | 100 |
Preparing Stock Solutions
for AEBSF
The following data is based on the product molecular weight 239.69
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.17 mL | 20.86 mL | 41.72 mL |
| 5 mM | 0.83 mL | 4.17 mL | 8.34 mL |
| 10 mM | 0.42 mL | 2.09 mL | 4.17 mL |
| 50 mM | 0.08 mL | 0.42 mL | 0.83 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Saw Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease. PLoS ONE 2012 PMID: 22829914
- Diatchuk Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds. J.Biol.Chem. 1997 PMID: 9148950
Product Specific Notices for AEBSF
For research use only
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