ACPT-I

Name: ACPT-I
Brand: Tocris Bioscience
SKU: 1111

Tocris Bioscience, part of Bio-Techne | Catalog # 1111

Citations (9)

COA / SDS

Group III mGlu agonist

Discontinued Product

1111 has been discontinued. View all Group III mGluR Agonists products.

Key Product Details

Description:	Group III mGlu agonist
Chemical Name:	(1S,3R,4S)-1-Aminocyclopentane-1,3,4-tricarboxylic acid
Molecular Weight:	217.18

View Full Technical Details for ACPT-I

Technical Data
Citations

Biological Activity for ACPT-I

ACPT-I is a agonist for group III mGlu receptors (EC₅₀ values are 7.2 and 8.2 μM for mGlu_4a and mGlu₈ respectively). Anticonvulsant in mice.

Licensing Information

Sold with the permission of the CNRS

Technical Data for ACPT-I

M. Wt	217.18
Formula	C₈H₁₁NO₆
Storage	Desiccate at -20°C
CAS Number	194918-76-8
PubChem ID	4302960
InChi Key	JARNORYOPMINDY-UHFFFAOYSA-N
Smiles	N[C@]1([C@](O)=O)C[C@@H]([C@](O)=O)[C@@H]([C@@](O)=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for ACPT-I

References are publications that support the biological activity of the product.

Chapman Anticonvulsant activity of a mGlu_4α receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid. Eur.J.Pharmacol. 2001 PMID: 11476756
De Colle Pharmacological characterization of the rat metabotropic glutamate receptor 8a revealed strong similarities and slight differences with the type 4a receptor. Eur.J.Pharmacol. 2000 PMID: 10771029
Acher Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes. J.Med.Chem. 1997 PMID: 9301676