ABT 594 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 6576

Selective α4β2 nAChR agonist
Catalog #
Availability
Size / Price
Qty
6576/10
6576/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Selective α4β2 nAChR agonist

Alternative Names

Tebanicline

View all Nicotinic (a4b2) Receptor Agonists »

Product Description

ABT 594 hydrochloride is a selective α4β2 nAChR agonist (EC50 = 140 nM for human α4β2 nAChRs, in vitro). Exhibits >900-fold selectivity for α4β2 nAChRs over other neurotransmitter receptors. Displays analgesic properties in various animal models of pain. Potentiates gabapentin mediated analgesia. Also demonstrates cognitive enhancement effects in rodent model of attention deficit.

Product Specifications

Molecular Weight

235.11

Formula

C9H11ClN2O.HCL

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride

CAS Number

203564-54-9

PubChem ID

72193963

InChI Key

GYVARJONEFSAJB-OGFXRTJISA-N

SMILES

ClC1=NC=C(C=C1)OC[C@H]2CCN2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 23.51 100
DMSO 23.51 100

Preparing Stock Solutions for ABT 594 hydrochloride

The following data is based on the product molecular weight 235.11

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.25 mL 21.27 mL 42.53 mL
5 mM 0.85 mL 4.25 mL 8.51 mL
10 mM 0.43 mL 2.13 mL 4.25 mL
50 mM 0.09 mL 0.43 mL 0.85 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for ABT 594 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ABT 594 hydrochloride

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.