A 68930 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 1534
Potent and selective D1-like agonist
Key Product Details
Description
Potent and selective D1-like agonist
Product Description
A 68930 hydrochloride is a potent and selective D1-like dopamine receptor agonist (EC50 values are 2.1 and 3910 nM for D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.Product Specifications
Molecular Weight
307.78
Formula
C16H17NO3.HCl
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
cis-(±)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
CAS Number
130465-39-3
PubChem ID
9904672
InChI Key
PQPGUUQPTSMLKU-YYLIZZNMSA-N
SMILES
OC1=C(O)C=CC2=C1C[C@@H]([C@]3=CC=CC=C3)O[C@H]2CN.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.39 | 50 |
Preparing Stock Solutions
for A 68930 hydrochloride
The following data is based on the product molecular weight 307.78
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 6.50 mL | 32.49 mL | 64.98 mL |
| 2.5 mM | 1.30 mL | 6.50 mL | 13.00 mL |
| 5 mM | 0.65 mL | 3.25 mL | 6.50 mL |
| 25 mM | 0.13 mL | 0.65 mL | 1.30 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kebabian A68930: a potent and specific agonist for the D-1 DA receptor. Am.J.Hypertens. 1990 PMID: 2143387
- Quaglia (1R,3S)-1-(Aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist. J.Med.Chem. 1990 PMID: 1977907
- Deveney and Waddingto Psychopharmacological distinction between novel full-efficacy "D1-like" DA receptor agonists. Pharmacol.Biochem.Behav. 1997 PMID: 9300618
Product Specific Notices for A 68930 hydrochloride
For research use only
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