7-Nitroindazole
Tocris Bioscience, part of Bio-Techne | Catalog # 0602
Non-selective NOS inhibitor
Discontinued Product
0602 has been discontinued.
View all Additional NOS Inhibitors products.
Product Description
7-Nitroindazole is a reversible, competitive and non-selective NOS inhibitor.Monosodium Salt also available.
Product Specifications
Molecular Weight
163.14
Formula
C7H5N3O2
Storage
Desiccate at -20°C
Purity
≥98% (HPLC)
CAS Number
2942-42-9
PubChem ID
1893
InChI Key
PQCAUHUKTBHUSA-UHFFFAOYSA-N
SMILES
[O-][N+](=O)C1=C2NN=CC2=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 100 | ||
| Ethanol | 3.26 | 20 |
Preparing Stock Solutions
for 7-Nitroindazole
The following data is based on the product molecular weight 163.14
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.13 mL | 30.65 mL | 61.30 mL |
| 5 mM | 1.23 mL | 6.13 mL | 12.26 mL |
| 10 mM | 0.61 mL | 3.06 mL | 6.13 mL |
| 50 mM | 0.12 mL | 0.61 mL | 1.23 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Moore and Handy Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 1997 PMID: 9226999
- Moore 7-nitroindazole, an inhibitor of nitric oxide synthase, exhibits antinociceptive activity in the mouse without increasing blood pressure. Br.J.Pharmacol. 1993 PMID: 7680591
- Moore Characterisation of the novel nitric oxide synthase inhibitor 7-nitroindazole and related indazoles: antinociceptive and cardiovascular effects. Br.J.Pharmacol. 1993 PMID: 7693278
- Babbedge Inhibition of rat cerebellar nitric oxide synthase by 7-nitroindazole and related substituted indazoles. Br.J.Pharmacol. 1993 PMID: 7693279
Product Specific Notices for 7-Nitroindazole
For research use only
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