4-P-PDOT
Tocris Bioscience, part of Bio-Techne | Catalog # 1034
MT2 antagonist
Key Product Details
Description
MT2 antagonist
Alternative Names
AH 024
Product Description
4-P-PDOT is a melatonin receptor antagonist, >300-fold selective for the MT2 (vs MT1) subtype.Product Specifications
Molecular Weight
279.38
Formula
C19H21NO
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
cis-4-Phenyl-2-propionamidotetralin
CAS Number
620170-78-7
PubChem ID
3976006
InChI Key
RCYLUNPFECYGDW-UHFFFAOYSA-N
SMILES
CCC(=O)NC1CC(C2=CC=CC=C2)C2=C(C1)C=CC=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.94 | 100 | |
| Ethanol | 27.94 | 100 |
Preparing Stock Solutions
for 4-P-PDOT
The following data is based on the product molecular weight 279.38
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.58 mL | 17.90 mL | 35.79 mL |
| 5 mM | 0.72 mL | 3.58 mL | 7.16 mL |
| 10 mM | 0.36 mL | 1.79 mL | 3.58 mL |
| 50 mM | 0.07 mL | 0.36 mL | 0.72 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Dubocovich Melatonin receptors: are there multiple subtypes? TiPS 1995 PMID: 7762083
- Dubocovich Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroceptor. Naunyn Schmiedebergs Arch.Pharmacol. 1997 PMID: 9089668
Product Specific Notices for 4-P-PDOT
For research use only
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