3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0918
Potent dopamine uptake inhibitor
Discontinued Product
0918 has been discontinued.
View all Dopamine Transporter Inhibitors products.
Key Product Details
Description
Potent dopamine uptake inhibitor
Product Description
3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride is a potent inhibitor of dopamine uptake and transport (Ki = 11.8 nM).Product Specifications
Molecular Weight
379.88
Formula
C21H23F2NO.HCl
Storage
Store at RT
CAS Number
202646-03-5
PubChem ID
45260711
InChI Key
YOORVSGDAHWVMC-UHFFFAOYSA-N
SMILES
Cl.CN1C2CCC1CC(C2)OC(C1=CC=C(F)C=C1)C1=CC=C(F)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 37.99 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 379.88
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.63 mL | 13.16 mL | 26.32 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
| 10 mM | 0.26 mL | 1.32 mL | 2.63 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.53 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Newman Novel 4'-substituted and 4'4"-disubstituted 3α-(diphenylmethoxy)tropane analogs as potent and selective DA uptake inhibitors. J.Med.Chem. 1995 PMID: 7562926
- Newman Novel 3α-(diphenylmethoxy)tropane analogs: potent DA uptake inhibitors without cocaine-like behavioural profiles. J.Med.Chem. 1994 PMID: 8057273
Product Specific Notices
For research use only
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