2-Methylthioadenosine diphosphate trisodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 1624

Potent agonist at P2Y1, P2Y12 and P2Y13
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Key Product Details

Description

Potent agonist at P2Y1, P2Y12 and P2Y13

Alternative Names

2-(Methylthio)adenosine 5'-diphosphate,2-Methylthio-ADP,MeSADP

View all P2Y Receptor Agonists »

Product Description

2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13). Induces aggregation of, and inhibits cAMP accumulation in, platelets in vitro.

Product Specifications

Molecular Weight

539.24

Formula

C11H14N5Na3O10P2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-(Methylthio)adenosine-5'-(trihydrogen diphosphate) trisodium salt

CAS Number

475193-31-8

PubChem ID

52942441

InChI Key

DYNGCIHMNWOBSU-MSQVLRTGSA-K

SMILES

O[C@@H]1[C@@H](COP(OP([O-])([O-])=O)([O-])=O)O[C@@H](N3C2=NC(SC)=NC(N)=C2N=C3)[C@@H]1O.[Na+].[Na+].[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in water (supplied pre-dissolved at a concentration of 10mM)

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Background References

References are publications that support the biological activity of the product.

Product Documents for 2-Methylthioadenosine diphosphate trisodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 2-Methylthioadenosine diphosphate trisodium salt

For research use only

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