Simple Plex Discovery Control for Human Uromodulin

Name: Simple Plex Discovery Control for Human Uromodulin
Brand: ProteinSimple
SKU: 897694

ProteinSimple, part of Bio-Techne | Catalog # 897694

Product Datasheet / COA

Control for use with Human Uromodulin Simple Plex Assay Cartridge Kit

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Technical Data
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Summary for Simple Plex Discovery Control for Human Uromodulin

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human Uromodulin concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Uromodulin (also Tamm-Horsfall glycoprotein or THP) is an 85 - 95 kDa urinary glycoprotein. It is secreted by renal tubule epithelium, acts as a binding protein for IL-1, TNF-α and C1q, activates resting monocytes and promotes neutrophil phagocytosis. Uromodulin forms high molecular weight oligomers that line the kidney tubules. Human Uromodulin is GPI-linked. Human Uromodulin is 78% aa identical to mouse Uromodulin.

Product Specifications for Simple Plex Discovery Control for Human Uromodulin

Species

Human

Preparation & Storage

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: Uromodulin

Item	Value
Entrez Gene IDs	7369 (Human); 22242 (Mouse); 25128 (Rat)
Alternate Names	ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP, Tamm-Horsfall glycoprotein, Tamm-Horsfall urinary glycoprotein, UMOD, Uromodulin, Uromucoid, uromodulin (uromucoid, Tamm-Horsfall glycoprotein)

Product Documents for Simple Plex Discovery Control for Human Uromodulin

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