Summary for Simple Plex Discovery Control for Human CCL11/Eotaxin
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human CCL11/Eotaxin concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
CCL11/Eotaxin is a chemokine that interacts with CCR3 to induce eosinophil, basophil, dendritic cell, and Th2 cell chemoattraction during inflammatory and allergic reactions. Its production is upregulated in airway epithelium, alveolar macrophages, eosinophils, smooth muscle cells, chondrocytes, and fibroblasts following allergen or inflammatory challenge. CCL11 is also involved in the growth of myeloid cell progenitors and the differentiation of mast cells.
Product Specifications for Simple Plex Discovery Control for Human CCL11/Eotaxin
Species
Human
Preparation & Storage
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt. • Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended. • Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: CCL11/Eotaxin
Item
Value
Entrez Gene IDs
6356 (Human); 20292 (Mouse)
Alternate Names
C-C motif chemokine 11, CCL11, Eosinophil chemotactic protein, Eotaxin, MGC22554, SCYA11Small-inducible cytokine A11, chemokine (C-C motif) ligand 11, eotaxin-1, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
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