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Simple Plex Control for Human Proprotein Convertase 9/PCSK9

ProteinSimple, part of Bio-Techne | Catalog # 898101

Control for use with Human Proprotein Convertase 9/PCSK9 Simple Plex Cartridge Kit
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898101

Key Product Details

Species

Human

Applications

Control, Simple Plex Automated Immunoassay

Product Summary for Simple Plex Control for Human Proprotein Convertase 9/PCSK9

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human Proprotein Convertase 9/PCSK9 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Formulation, Preparation, and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: Proprotein Convertase 9/PCSK9

PCSK9 (Proprotein Convertase 9, is a serine endoprotease that is highly expressed in the liver, intestine, and kidney. PCSK9 promotes the degradation of low density lipoprotein receptor (LDLR) by inducing receptor degradation in the lysosome following its internalization. PCSK9 regulates the amounts of LDLR in the circulation and hence, modulates cholesterol levels. Nonsense or loss-of-function mutations in PCSK9 are associated with decreased plasma LDL cholesterol levels.

Alternate Names

FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, PCSK9

Entrez Gene IDs

255738 (Human); 100102 (Mouse); 298296 (Rat); 102142788 (Cynomolgus Monkey)

Gene Symbol

PCSK9

Additional Proprotein Convertase 9/PCSK9 Products

Product Documents for Simple Plex Control for Human Proprotein Convertase 9/PCSK9

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Simple Plex Control for Human Proprotein Convertase 9/PCSK9

For research use only

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