Summary for Simple Plex Control for Human HGFR/c-MET
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human HGFR/c-MET concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
HGF receptor, a product of the proto-oncogene c-met, is a heterodimeric transmembrane glycoprotein that is a receptor-type tyrosine kinase. c-MET is synthesized as a single-chain precursor (pr170) which undergoes post-translational glycosylation and proteolytic cleavage to give rise to the heterodimeric mature form.
Product Specifications for Simple Plex Control for Human HGFR/c-MET
Species
Human
Applications
Control, Simple Plex Automated Immunoassay
Source
N/A
Preparation & Storage
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt. • Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended. • Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: HGFR/c-MET
Item
Value
Long Name
Hepatocyte Growth Factor Receptor
Entrez Gene IDs
4233 (Human); 17295 (Mouse)
Alternate Names
AUTS9, EC 2.7.10, EC 2.7.10.1, HGF R, HGF receptor, HGF/SF receptor, HGFR, MET, Met (c-Met), Proto-oncogene c-Met, RCCP2, SF receptor, Scatter factor receptor, Tyrosine-protein kinase Met, c-MET, cMET, hepatocyte growth factor receptor, met proto-oncogene (hepatocyte growth factor receptor), met proto-oncogene tyrosine kinase, oncogene MET
