Simple Plex Control for Human CD40 Ligand/TNFSF5

Name: Simple Plex Control for Human CD40 Ligand/TNFSF5
Brand: ProteinSimple
SKU: 897160

ProteinSimple, part of Bio-Techne | Catalog # 897160

Product Datasheet / COA

Control for use with Human CD40 Ligand/TNFSF5 Simple Plex Assay Cartridge Kit

Key Product Details

Technical Data
Citations

Summary for Simple Plex Control for Human CD40 Ligand/TNFSF5

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human CD40 Ligand/TNFSF5 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

CD40 Ligand, also known as TNFSF5, CD154, TRAP, and gp39, is a trimeric protein that is expressed in transmembrane and soluble forms. It is expressed by many immune cell types as well as by endothelial and smooth muscle cells of the vasculature. It binds to CD40 on antigen presenting cells, platelets, and endothelial and epithelial cells, leading to enhanced B cell activation and T cell dependent humoral immune responses. CD40 Ligand dysregulation contributes to immune pathology in AIDS, atherosclerosis, atherothrombosis, and restenosis.

Product Specifications for Simple Plex Control for Human CD40 Ligand/TNFSF5

Species	Human
Applications	Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: CD40 Ligand/TNFSF5

Entrez Gene IDs

959 (Human); 21947 (Mouse); 84349 (Rat)

Alternate Names

CD154, CD154 antigen, CD40 Ligand, CD40 antigen ligand, CD40-L, CD40L, CD40LG, CD40LIGM, HIGM1, T-B cell-activating molecule, T-BAM, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TNFSF5IMD3, TRAP, TRAPtumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome), Tumor necrosis factor ligand superfamily member 5, gp39, hCD40L, tumor necrosis factor (ligand) superfamily member 5

Product Documents for Simple Plex Control for Human CD40 Ligand/TNFSF5

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