Recombinant Mammal TNF RI/TNFRSF1A Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-57423

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NBP3-57423-25ug
NBP3-57423-5ug
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Key Product Details

Conjugate

Unconjugated

Applications

Western Blot, ELISA, Cell Culture

View all TNF RI/TNFRSF1A Proteins and Enzymes »

Product Specifications

Description

A recombinant protein corresponding to 157 aa of Mammal TNF RI/TNFRSF1A.

Source: Yeast

Amino Acid Sequence: LRSSSKTSSN KPVAHVVANL STQGQLRWLN TYANTLLANS VKLEDNQLVV PTDGLYLIYS QVLFRGQGCP STHLFLTHTI SRIAVSYPTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYQ GGVFQLEKGD RLSAEINLPD YLDFAESGQV YFGIIAL (157)

Stable for up to 12 months from date of receipt at -20C. Stable for 3 months when stored in working aliquots with a carrier protein at -20C. Avoid repeated freeze/thaw cycles.

Purity

>98%, by SDS-PAGE

Endotoxin Level

No affinity tags & naturally endotoxin-free

Predicted Molecular Mass

17.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Enzyme-linked Immunosorbent Spot (ELISPOT)
ELISA Standard (Matched Pair) (ELISA(Sta))

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation and Storage

NBP3-57423
Formulation Lyophilized in 1-5X PBS containing 10% Trehalose
Preservative 10% Trehalose
Reconstitution Reconstitute in sterile PBS with at least 0.1% carrier protein
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: TNF RI/TNFRSF1A

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for Recombinant Mammal TNF RI/TNFRSF1A Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Recombinant Mammal TNF RI/TNFRSF1A Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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