Recombinant Mouse IL-4 Protein Best Seller
Catalog # 404-ML | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | E. coli |
Accession #: | P07750 |
Applications: | Bioactivity |
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Citations for Recombinant Mouse IL-4 Protein (421)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Mouse IL-4 Protein include:
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Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLu et al. (2023-05-22), Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages Journal of translational medicine
PMID: 37217897 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCheu et al. (2023-05-05), Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development Science advances
PMID: 37146141 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShang et al. (2023-05-05), MTHFD2 reprograms macrophage polarization by inhibiting PTEN Cell reports
PMID: 37149861 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKurosaka et al. (2023-04-29), IL-4 Signaling Promotes Myoblast Differentiation and Fusion by Enhancing the Expression of MyoD, Myogenin, and Myomerger Cells
PMID: 37174683 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayArpa et al. (2023-04-11), Distinct Responses to IL4 in Macrophages Mediated by JNK Cells
PMID: 37190036 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Huang et al. (2023-03-30), The RNA-binding protein hnRNP F is required for the germinal center B cell response Nature Communications, 2023-014(1):1731.
PMID: 36997512 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKA Read et al. (2023-03-24), Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity Nature Communications, 2023-014(1):1652.
PMID: 36964178 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWL Yang et al. (2023-02-16), Nsun2 coupling with RoRgammat shapes the fate of Th17 cells and promotes colitis Nature Communications, 2023-014(1):863.
PMID: 36792629 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Beckmann et al. (2023-02-08), Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model Journal of Neuroinflammation, 2023-020(1):29.
PMID: 36755323 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRK Gurram et al. (2023-02-02), Crosstalk between ILC2s and Th2 cells varies among mouse models Cell Reports, 2023-042(2):112073.
PMID: 36735533 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2023-01-30), CCR7 Mediates Dendritic-Cell-Derived Exosome Migration and Improves Cardiac Function after Myocardial Infarction Pharmaceutics, 2023-015(2).
PMID: 36839783 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Li et al. (2023-01-30), Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress Journal of Neuroinflammation, 2023-020(1):16.
PMID: 36710351 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWH Lee et al. (2023-01-29), Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway International Journal of Molecular Sciences, 2023-024(3).
PMID: 36768873 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMK Park et al. (2023-01-27), Toll-like receptor 2 mediates Acanthamoeba-induced allergic airway inflammatory response in mice PloS Neglected Tropical Diseases, 2023-017(1):e0011085.
PMID: 36706056 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Mironov et al. (2023-01-19), Rac1 controls cell turnover and reversibility of the involution process in postpartum mammary glands PloS Biology, 2023-021(1):e3001583.
PMID: 36656812 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Liu et al. (2023-01-18), Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity Cell Reports, 2023-042(1):111991.
PMID: 36656709 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKC Huang et al. (2023-01-03), A Novel Engineered AAV-based Neoantigen Vaccine in Combination with Radiotherapy Eradicates Tumors Cancer Immunology Research, 2023-00(0).
PMID: 36315960 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWH Lee et al. (2023), Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway International Journal of Molecular Sciences, 24(3).
PMID: 36768873 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Hu et al. (2022-12-25), Role of Adenylyl Cyclase Type 7 in Functions of BV-2 Microglia International Journal of Molecular Sciences, 2022-124(1).
PMID: 36613790 -
Species: Mouse
BE Clausen et al. (2022-12-23), Guidelines for mouse and human DC functional assays European Journal of Immunology, 2022-10(0).
PMID: 36563126 -
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassayCY Chang et al. (2022-11-16), Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer Science Advances, 2022-18(46):eabq0615.
PMID: 36383649 -
Species: Mouse, Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassayY Hou et al. (2022-11-15), FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism Cell Reports, 2022-141(7):111668.
PMID: 36384126 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySA Park et al. (2022-10-14), Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation Nature Communications, 2022-113(1):6069.
PMID: 36241625 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Cho et al. (2022-10-10), Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target Nature Communications, 2022-113(1):5974.
PMID: 36216803 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAP Shaik et al. (2022-10-06), Detection of Radiolabeled Inflammatory Cell Macrophage Subpopulations in Chronic Respiratory Diseases: Results from Preliminary Analyses BioMed Research International, 2022-12022(0):9470845.
PMID: 36246991 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKC Fernandez et al. (2022-10-03), The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes Elife, 2022-111(0).
PMID: 36190107 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Liu et al. (2022-09-29), Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling Mediators of Inflammation, 2022-02022(0):3441357.
PMID: 36211988 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureSI Tsukumo et al. (2022-08-24), AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination Science Advances, 2022-08(34):eabq0008.
PMID: 36001653 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Inoue et al. (2022-08-19), Macrophage-Specific, Mafb-Deficient Mice Showed Delayed Skin Wound Healing International Journal of Molecular Sciences, 2022-023(16).
PMID: 36012611 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayEA Kowalski et al. (2022-08-08), Monocyte pro-inflammatory phenotypic control by Ephrin type-A receptor 4 mediates neural tissue damage JCI Insight, 2022-00(0).
PMID: 35737458 -
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western BlotC Vasavda et al. (2022-08-03), Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain Science Advances, 2022-08(31):eabo5633.
PMID: 35921423 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Mo et al. (2022-07-11), Intratracheal administration of mesenchymal stem cells modulates lung macrophage polarization and exerts anti-asthmatic effects Scientific Reports, 2022-012(1):11728.
PMID: 35821386 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Guo et al. (2022-07-04), Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation Theranostics, 2022-012(11):5220-5236.
PMID: 35836819 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMK Ameka et al. (2022-07-03), An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload International Journal of Molecular Sciences, 2022-023(13).
PMID: 35806422 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Mary et al. (2022-07-01), Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects Cancer Immunology Research, 2022-00(0):OF1-OF17.
PMID: 35612500 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Yin et al. (2022-06-24), Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32 Cell Death Disease, 2022-06-24;13(6):567.
PMID: 35739102 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJH Lee et al. (2022-05-31), SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization Journal of advanced research, 2022-00(0).
PMID: 35659922 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Jin et al. (2022-05-31), Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis Cell Death Disease, 2022-05-31;13(5):512.
PMID: 35641492 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAP Leinroth et al. (2022-05-10), Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations Cell Reports, 2022-039(6):110785.
PMID: 35545045 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Ming-Chin et al. (2022-04-19), Type I interferon antagonism of the JMJD3-IRF4 pathway modulates macrophage activation and polarization Cell Reports, 2022-039(3):110719.
PMID: 35443173 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureMM LaRue et al. (2022-04-11), Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer Proceedings of the National Academy of Sciences of the United States of America, 2022-0119(16):e2119168119.
PMID: 35412885 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Qu et al. (2022-03-31), Self-assembled BPIV3 nanoparticles can induce comprehensive immune responses and protection against BPIV3 challenge by inducing dendritic cell maturation in mice Veterinary Microbiology, 2022-0268(0):109415.
PMID: 35395543 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCJ Ortiz-Boni et al. (2022-03-08), Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity International Journal of Molecular Sciences, 2022-023(6).
PMID: 35328324 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJD Hathaway-S et al. (2022-02-22), Commensal oral microbiota induces osteoimmunomodulatory effects separate from systemic microbiome in mice JCI Insight, 2022-00(0).
PMID: 35077397 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Mirman et al. (2022-01-13), 53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polalpha-primase fill-in synthesis Nature Cell Biology, 2022-024(1):51-61.
PMID: 35027730 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Zhao et al. (2021-12-30), CircN4bp1 Facilitates Sepsis-Induced Acute Respiratory Distress Syndrome through Mediating Macrophage Polarization via the miR-138-5p/EZH2 Axis Mediators of Inflammation, 2021-12021(0):7858746.
PMID: 35002536 -
Species: Mouse
Sample Types: Whole Cells
Applications: PolarizationX Xiao et al. (2021-12-15), Dihydroartemisinin inhibits Lewis Lung carcinoma progression by inducing macrophages M1 polarization via AKT/mTOR pathway International immunopharmacology, 2021-1103(0):108427.
PMID: 34922249 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Chen et al. (2021-12-14), Immunosuppressive effect of Columbianadin on maturation, migration, allogenic T cell stimulation and phagocytosis capacity of TNF-alpha induced dendritic cells Journal of ethnopharmacology, 2021-1285(0):114918.
PMID: 34919989 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Di Pietro et al. (2021-11-29), Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection Nature Immunology, 2021-10(0).
PMID: 34845392 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Feng et al. (2021-11-24), FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation Nature, 2021-10(0).
PMID: 34819670 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHM Shen et al. (2021-11-23), Loop extrusion promotes an alternate pathway for isotype switching Cell Reports, 2021-137(8):110059.
PMID: 34818547 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Long et al. (2021-11-18), CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity Nature, 2021-10(0).
PMID: 34795452 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKM Deng et al. (2021-11-17), Deleterious Role of Th9 Cells in Pulmonary Fibrosis Cells, 2021-110(11).
PMID: 34831433 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Shi et al. (2021-11-08), The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons Journal of Neuroinflammation, 2021-118(1):261.
PMID: 34749758 -
Species: Mouse
Sample Types: Whole Cells
Applications: Differentiation, DifferentiationJM Motta et al. (2021-10-04), Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation Biomedicines, 2021-19(10).
PMID: 34680504 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Muto et al. (2021-09-21), Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis Scientific Reports, 2021-011(1):18778.
PMID: 34548598 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Hu et al. (2021-09-21), Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling Cell Reports, 2021-036(12):109726.
PMID: 34551302 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Qadri et al. (2021-09-14), Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration Arthritis Research Therapy, 2021-09-14;23(1):241.
PMID: 34521469 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Dai et al. (2021-09-06), Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease Brain, Behavior, and Immunity, 2021-098(0):337-348.
PMID: 34500034 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayF Zhao et al. (2021-08-05), ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection Nature Cell Biology, 2021-023(8):894-904.
PMID: 34354233 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNR Nabar et al. (2021-07-27), LRRK2 is required for CD38-mediated NAADP-Ca2+ signaling and the downstream activation of TFEB (transcription factor EB) in immune cells Autophagy, 2021-00(0):19-Jan.
PMID: 34313548 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Wu et al. (2021-07-23), Hemin-primed dendritic cells suppress allergic airway inflammation through releasing extracellular vesicles Journal of leukocyte biology, 2021-00(0).
PMID: 34296788 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySS Yerneni et al. (2021-07-13), Pneumococcal Extracellular Vesicles Modulate Host Immunity MBio, 2021-00(0):e0165721.
PMID: 34253061 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Ortega-Mol et al. (2021-07-13), Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs Cell Reports, 2021-036(2):109372.
PMID: 34260908 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Wang et al. (2021-06-18), ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication Science Advances, 2021-07(25).
PMID: 34144977 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Zhou et al. (2021-06-16), m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity Science Advances, 2021-07(25).
PMID: 34134995 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Kurosaka et al. (2021-05-29), Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis Skeletal Muscle, 2021-011(1):14.
PMID: 34051858 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Lu et al. (2021-05-25), MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-&kappaB pathway Cell Death Disease, 2021-05-25;12(6):533.
PMID: 34031369 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Feng et al. (2021-04-28), Docosahexaenoic acid ameliorates autoimmune inflammation by activating GPR120 signaling pathway in dendritic cells International immunopharmacology, 2021-097(0):107698.
PMID: 33932699 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Luo et al. (2021-04-21), Light-induced dynamic RGD pattern for sequential modulation of macrophage phenotypes Bioactive materials, 2021-06(11):4065-4072.
PMID: 33997493 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Wan et al. (2021-04-15), Activation of 4-1BB signaling in bone marrow stromal cells triggers bone loss via the p-38 MAPK-DKK1 axis in aged mice Experimental Molecular Medicine, 2021-04-15;0(0).
PMID: 33859350 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2021-04-14), Immune modulation mediated by extracellular vesicles of intestinal organoids is disrupted by opioids Mucosal Immunology, 2021-00(0).
PMID: 33854193 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Wang et al. (2021-04-06), Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity Cell Reports, 2021-035(1):108948.
PMID: 33826900 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTJ Kopper et al. (2021-03-18), The effects of myelin on macrophage activation are phenotypic specific via cPLA2 in the context of spinal cord injury inflammation Scientific Reports, 2021-011(1):6341.
PMID: 33737707 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Sripada et al. (2021-03-08), Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases PloS Biology, 2021-019(3):e3001063.
PMID: 33684096 -
Species: Transgenic Mouse
Sample Types: Spheroid
Applications: BioassayAE Engler et al. (2020-12-29), Airway-Associated Macrophages in Homeostasis and Repair Cell Reports, 2020-133(13):108553.
PMID: 33378665 -
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassayL Kealy et al. (2020-12-15), The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses Cell Reports, 2020-133(11):108504.
PMID: 33326791 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureRK Arya et al. (2020-12-04), Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation The Journal of Biological Chemistry, 2020-10(0).
PMID: 33262217 -
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassayA Baniahmad et al. (2020-11-24), The frequency of follicular T helper cells differs in acute and chronic neuroinflammation Sci Rep, 2020-110(1):20485.
PMID: 33235306 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureR Yang et al. (2020-11-23), Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathway J Transl Med, 2020-118(1):444.
PMID: 33228696 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySH Shin et al. (2020-11-08), A Novel Selective Sphingosine Kinase 2 Inhibitor, HWG-35D, Ameliorates the Severity of Imiquimod-Induced Psoriasis Model by Blocking Th17 Differentiation of Na�ve CD4 T Lymphocytes Int J Mol Sci, 2020-121(21).
PMID: 33171607 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDM de Graaf et al. (2020-10-28), Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease Cytokine, 2020-1137(0):155334.
PMID: 33128926 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayVK Rangasami et al. (2020-10-27), Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization Carbohydrate polymers, 2020-1254(0):117291.
PMID: 33357860 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCY Han et al. (2020-09-24), Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its anti-inflammatory properties JCI Insight, 2020-00(0).
PMID: 32970631 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Francica et al. (2020-08-25), Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining Cell Rep, 2020-032(8):108068.
PMID: 32846126 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Tur et al. (2020-08-25), Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity Cell Rep, 2020-032(8):108079.
PMID: 32846136 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAJ Nelson et al. (2020-08-20), Lipid mediators and biomarkers associated with type 1 diabetes development JCI Insight, 2020-05(16).
PMID: 32814707 -
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell CultureMA Maqbool et al. (2020-08-18), Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation Cell Rep, 2020-032(7):108048.
PMID: 32814051 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJM Inclan-Ric et al. (2020-08-17), Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition Nat. Immunol., 2020-00(0).
PMID: 32807943 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Tu et al. (2020-08-13), TGF-beta2 interfering oligonucleotides used as adjuvants for microbial vaccines J. Leukoc. Biol., 2020-00(0).
PMID: 32794350 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell CultureM Koide et al. (2020-08-13), Sclerostin expression in trabecular bone is downregulated by osteoclasts Sci Rep, 2020-010(1):13751.
PMID: 32792620 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJPM Luiz et al. (2020-08-03), MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression J. Leukoc. Biol., 2020-00(0).
PMID: 32745297 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Kim et al. (2020-07-29), Immunoglobulin Class Switch Recombination is initiated by rare cytosine deamination events at switch regions Mol. Cell. Biol., 2020-00(0).
PMID: 32513818 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureA Jandke et al. (2020-07-28), Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial &gamma&delta T cell compartments Nat Commun, 2020-011(1):3769.
PMID: 32724083 -
Species: Mouse
Sample Types: Primary Cells
Applications: Cell CultureD Prantner et al. (2020-07-17), Classically activated mouse macrophages produce methylglyoxal that induces a TLR4- and RAGE-independent proinflammatory response J. Leukoc. Biol., 2020-00(0).
PMID: 32678947 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureLJ Wang et al. (2020-07-17), Isoliquiritigenin ameliorates caerulein-induced chronic pancreatitis by inhibiting the activation of PSCs and pancreatic infiltration of macrophages J. Cell. Mol. Med., 2020-00(0).
PMID: 32678498 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayB Mahata et al. (2020-07-17), Tumors induce de novo steroid biosynthesis in T cells to evade immunity Nat Commun, 2020-011(1):3588.
PMID: 32680985 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Yan et al. (2020-06-30), T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation Cell Rep, 2020-031(13):107820.
PMID: 32610123 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCY Han et al. (2020-06-30), Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity Cell Rep, 2020-031(13):107818.
PMID: 32610121 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAP Ng et al. (2020-06-15), An Erg-driven transcriptional program controls B cell lymphopoiesis Nat Commun, 2020-011(1):3013.
PMID: 32541654 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Kubota et al. (2020-05-27), Adjuvant activity of Mycobacteria-derived mycolic acids Heliyon, 2020-06(5):e04064.
PMID: 32490252 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryIS Kang et al. (2020-04-27), Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation Sci Rep, 2020-010(1):7024.
PMID: 32341385 -
Species: Human, Mouse
Sample Types: Whole Cells
Applications: BioassayW Lei et al. (2020-04-24), The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice Sci Rep, 2020-010(1):7004.
PMID: 32332865 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Zhu et al. (2020-04-22), Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb Stem Cell Res Ther, 2020-011(1):162.
PMID: 32321589 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureH Gan et al. (2020-04-01), B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response Sci Adv, 2020-06(14):eaay2793.
PMID: 32270032 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Lv et al. (2020-03-31), CXCL14 Overexpression Attenuates Sepsis-Associated Acute Kidney Injury by Inhibiting Proinflammatory Cytokine Production Mediators Inflamm., 2020-02020(0):2431705.
PMID: 32317861 -
Species: Mouse
Sample Types: bone marrow cells
Applications: Cell CultureW Lin et al. (2020-03-26), Radiation-induced small extracellular vesicles as "carriages" promote tumor antigen release and trigger antitumor immunity Theranostics, 2020-010(11):4871-4884.
PMID: 32308755 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureD Kazadi et al. (2020-03-12), Effects of senataxin and RNA exosome on B-cell chromosomal integrity Heliyon, 2020-06(3):e03442.
PMID: 32195383 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureE Meidan et al. (2020-03-12), Serine/threonine phosphatase PP2A is essential for optimal B cell function JCI Insight, 2020-05(5).
PMID: 32161189 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zhao et al. (2020-03-10), I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis Mediators Inflamm., 2020-02020(0):6947482.
PMID: 32256194 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureX Zhuang et al. (2020-03-10), mRNA Vaccines Encoding the HA Protein of Influenza A H1N1 Virus Delivered by Cationic Lipid Nanoparticles Induce Protective Immune Responses in Mice Vaccines (Basel), 2020-08(1).
PMID: 32164372 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDA Girón-Pére et al. (2020-03-02), Myo1e modulates the recruitment of activated B cells to inguinal lymph nodes J. Cell. Sci., 2020-00(0).
PMID: 31964710 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureML Li et al. (2020-02-28), HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization Respir. Res., 2020-021(1):62.
PMID: 32111211 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayB Maurer et al. (2020-01-31), High activation of STAT5A drives peripheral T-cell lymphoma and leukemia Haematologica, 2020-00(0).
PMID: 31123029 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureCB Lee et al. (2020-01-31), Anticancer Activity of Liquid Treated with Microwave Plasma-Generated Gas through Macrophage Activation Oxid Med Cell Longev, 2020-02020(0):2946820.
PMID: 32089766 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFC Simões et al. (2020-01-30), Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair Nat Commun, 2020-011(1):600.
PMID: 32001677 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJS Brunner et al. (2020-01-22), Environmental arginine controls multinuclear giant cell metabolism and formation Nat Commun, 2020-011(1):431.
PMID: 31969567 -
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassayH Yan et al. (2020-01-13), B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-kappaB Activation for Antibody Class-Switching J. Immunol., 2020-0204(5):1146-1157.
PMID: 31932498 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRK Arya et al. (2020-01-01), Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation The Journal of Biological Chemistry, 2020-0296(0):100129.
PMID: 33460921 -
Species: Mouse
Sample Types: Whole Cells
Applications: StimulationP Haase et al. (2019-12-15), Modulation of the humoral immune response by constitutively active STAT6 expression in murine B cells Eur. J. Immunol., 2019-10(0).
PMID: 31803941 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Khattar et al. (2019-12-13), Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy Nat Commun, 2019-110(1):5349.
PMID: 31836706 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureX Han et al. (2019-12-11), LncRNA PTPRE-AS1 modulates M2 macrophage activation and inflammatory diseases by epigenetic promotion of PTPRE Sci Adv, 2019-15(12):eaax9230.
PMID: 31844669 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMG Kim et al. (2019-12-05), Impact of aging on transition of acute kidney injury to chronic kidney disease Sci Rep, 2019-19(1):18445.
PMID: 31804508 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Mu et al. (2019-12-04), CD226 deficiency on regulatory T cells aggravates renal fibrosis via up-regulation of Th2 cytokines through miR-340 J. Leukoc. Biol., 2019-10(0).
PMID: 31802539 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS McLaughlin et al. (2019-10-25), Injectable human recombinant collagen matrices limit adverse remodeling and improve cardiac function after myocardial infarction Nat Commun, 2019-110(1):4866.
PMID: 31653830 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Mahmoudi et al. (2019-10-23), Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing Nature, 2019-1574(7779):553-558.
PMID: 31645721 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureGR Martin et al. (2019-10-03), Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice Sci Rep, 2019-19(1):14281.
PMID: 31582793 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureLP Garo et al. (2019-09-24), Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity Cell Rep, 2019-028(13):3353-3366.e5.
PMID: 31553906 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySS Dykes et al. (2019-09-17), Cathepsin L secretion by host and neoplastic cells potentiates invasion Oncotarget, 2019-010(53):5560-5568.
PMID: 31565189 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA El-Kenawi et al. (2019-08-16), Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer Br. J. Cancer, 2019-0121(7):556-566.
PMID: 31417189 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKS Cho et al. (2019-07-12), Dendritic cells and M2 macrophage play an important role in suppression of Th2-mediated inflammation by adipose stem cells-derived extracellular vesicles Stem Cell Res, 2019-039(0):101500.
PMID: 31344653 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CulturePAM Cavalcante et al. (2019-07-10), Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein Mediators Inflamm., 2019-02019(0):9086758.
PMID: 31360120 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Zhao et al. (2019-07-05), Anti-cervical carcinoma effect of Portulaca oleracea L. polysaccharides by oral administration on intestinal dendritic cells BMC Complement Altern Med, 2019-019(1):161.
PMID: 31277622 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJQ Yang et al. (2019-07-01), Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation J. Leukoc. Biol., 2019-00(0).
PMID: 31260596 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Liu et al. (2019-06-04), Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism PLoS Pathog., 2019-015(6):e1007817.
PMID: 31163079 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLR Waters et al. (2019-06-03), Ampk regulates IgD expression but not energy stress with B cell activation Sci Rep, 2019-09(1):8176.
PMID: 31160601 -
Species: Complex Species Category
Sample Types: Whole Cells
Applications: BioassayM Bolger-Mun et al. (2019-06-03), Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation Elife, 2019-08(0).
PMID: 31157616 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCP Hans et al. (2019-05-29), Transcriptomics Analysis Reveals New Insights into the Roles of Notch1 Signaling on Macrophage Polarization Sci Rep, 2019-09(1):7999.
PMID: 31142802 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMB Jones et al. (2019-05-23), CD45Rb-low effector T cells require IL-4 to induce IL-10 in FoxP3 Tregs and to protect mice from inflammation PLoS ONE, 2019-014(5):e0216893.
PMID: 31120919 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Ballester- et al. (2019-05-04), The Notch ligand DNER regulates macrophage IFN? release in chronic obstructive pulmonary disease EBioMedicine, 2019-00(0).
PMID: 31060902 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWF Yen et al. (2019-04-30), Distinct Requirements of CHD4 during B Cell Development and Antibody Response Cell Rep, 2019-027(5):1472-1486.e5.
PMID: 31042474 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Nicolas et al. (2019-04-26), Cutting Edge: ATM Influences Germinal Center Integrity J. Immunol., 2019-00(0).
PMID: 31028119 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayVV Kurilin et al. (2019-04-18), The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice J Immunol Res, 2019-02019(0):7029726.
PMID: 31143783 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYB Kim et al. (2019-03-06), Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasis Cell. Mol. Immunol., 2019-00(0).
PMID: 30842627 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Handa et al. (2019-03-05), Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis J. Leukoc. Biol., 2019-00(0).
PMID: 30835899 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPM Ryan et al. (2019-02-08), Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe BMC Microbiol., 2019-019(1):33.
PMID: 30736731 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Yasuda et al. (2019-02-01), Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation Nat Commun, 2019-010(1):549.
PMID: 30710091 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJN Pucella et al. (2019-01-25), The B Cell Activation-Induced miR-183 Cluster Plays a Minimal Role in Canonical Primary Humoral Responses J. Immunol., 2019-00(0).
PMID: 30683701 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLM Das et al. (2019-01-24), Vitamin D improves sunburns by increasing autophagy in M2 macrophages Autophagy, 2019-00(0):1-14.
PMID: 30661440 -
Species: Mouse
Sample Types: Whole Cells
K Paduch et al. (2019-01-21), Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1 J. Immunol., 2019-00(0).
PMID: 30665936 -
Species: Mouse
Sample Types: Whole Cells
AJ Freemerman et al. (2019-01-18), Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1 J. Immunol., 2019-00(0).
PMID: 30659108 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Fonseca et al. (2019-01-07), Group 2 innate lymphoid cells (ILC2) are regulated by stem cell factor during chronic asthmatic disease Mucosal Immunol, 2019-012(2):445-456.
PMID: 30617299 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJD Jones et al. (2018-12-31), Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis Neoplasia, 2018-121(2):172-184.
PMID: 30591422 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Amir et al. (2018-12-26), REV-ERB? Regulates TH17 Cell Development and Autoimmunity Cell Rep, 2018-125(13):3733-3749.e8.
PMID: 30590045 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Menolfi et al. (2018-12-17), Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA Nat Commun, 2018-19(1):5351.
PMID: 30559436 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Sugamata et al. (2018-12-17), Duox1 Regulates Primary B Cell Function under the Influence of IL-4 through BCR-Mediated Generation of Hydrogen Peroxide J. Immunol., 2018-10(0).
PMID: 30559322 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Simula et al. (2018-12-11), Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming Cell Rep, 2018-125(11):3059-3073.e10.
PMID: 30540939 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Chiu et al. (2018-12-10), The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes J. Immunol., 2018-10(0).
PMID: 30530594 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Liu et al. (2018-12-04), Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling Cell Res., 2018-10(0).
PMID: 30514903 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Sun et al. (2018-12-03), B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation Nat Commun, 2018-19(1):5127.
PMID: 30510188 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Skon-Hegg et al. (2018-12-03), LACC1 Regulates TNF and IL-17 in Mouse Models of Arthritis and Inflammation J. Immunol., 2018-10(0).
PMID: 30510070 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMT Rached et al. (2018-11-28), Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity Mol Metab, 2018-120(0):38-50.
PMID: 30553769 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Juban et al. (2018-11-20), AMPK Activation Regulates LTBP4-Dependent TGF-?1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy Cell Rep, 2018-125(8):2163-2176.e6.
PMID: 30463013 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAN Billin et al. (2018-11-13), HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury Skelet Muscle, 2018-18(1):35.
PMID: 30424786 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Becerra-Dí et al. (2018-10-10), Androgen and Androgen Receptor as Enhancers of M2 Macrophage Polarization in Allergic Lung Inflammation J. Immunol., 2018-10(0).
PMID: 30305328 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Wang et al. (2018-09-27), Mechanisms underlying immune tolerance caused by recombinant Echinococcus granulosus antigens Eg mMDH and Eg10 in dendritic cells PLoS ONE, 2018-013(9):e0204868.
PMID: 30261049 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Farruggia et al. (2018-09-19), Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners J. Nutr. Biochem., 2018-062(0):202-209.
PMID: 30308382 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Trezise et al. (2018-07-24), Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins Int J Mol Sci, 2018-019(8).
PMID: 30042348 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHA Ting et al. (2018-07-23), Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection Mucosal Immunol, 2018-00(0).
PMID: 30038214 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySM Noordermee et al. (2018-07-18), The shieldin complex mediates 53BP1-dependent DNA repair Nature, 2018-0560(7716):117-121.
PMID: 30022168 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Nowsheen et al. (2018-07-16), ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage Nat Commun, 2018-09(1):2736.
PMID: 30013081 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Youssif et al. (2018-07-01), Myeloid p38? signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis EMBO Mol Med, 2018-00(0).
PMID: 29907597 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Garcia-Bon et al. (2018-06-26), Endogenous protection from ischemic brain injury by preconditioned monocytes J. Neurosci., 2018-00(0).
PMID: 29946039 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBG Barwick et al. (2018-05-15), B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation Nat Commun, 2018-09(1):1900.
PMID: 29765016 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureR Ritzel et al. (2018-05-03), Chronic Alterations in Systemic Immune Function After Traumatic Brain Injury J. Neurotrauma, 2018-00(0).
PMID: 29421977 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCD Scharer et al. (2018-04-27), Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs Nat Commun, 2018-09(1):1698.
PMID: 29703886 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Andreas et al. (2018-04-06), A new RelB-dependent CD117+CD172a+murine dendritic cell subset preferentially induces Th2 differentiation and supports airway hyperresponses in vivo Eur. J. Immunol., 2018-00(0).
PMID: 29485182 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Chia et al. (2018-04-05), Enhanced Pro-Inflammatory Response of Macrophages to Interleukin-33 in an Allergic Environment Int. Arch. Allergy Immunol., 2018-00(0).
PMID: 29621782 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Han et al. (2018-03-29), Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression Cell, 2018-00(0).
PMID: 29606356 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Nowsheen et al. (2018-03-26), L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage Nat. Cell Biol., 2018-020(4):455-464.
PMID: 29581593 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Meyer Zu H et al. (2018-03-20), Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1 Immunity, 2018-048(3):556-569.e7.
PMID: 29562202 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Li et al. (2018-03-08), The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining Nat Commun, 2018-09(1):1006.
PMID: 29520062 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayB Sun et al. (2018-03-05), Characterization and allergic role of IL-33-induced neutrophil polarization Cell. Mol. Immunol., 2018-00(0).
PMID: 29503441 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Rangaraju et al. (2018-03-02), Differential Phagocytic Properties of CD45lowMicroglia and CD45highBrain Mononuclear Phagocytes-Activation and Age-Related Effects Front Immunol, 2018-09(0):405.
PMID: 29552013 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Lee et al. (2018-02-26), Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist PLoS ONE, 2018-013(2):e0193086.
PMID: 29481574 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Kerrinnes et al. (2018-02-20), Utilization of host polyamines in alternatively activated macrophages promotes chronic infection by Brucella abortus Infect. Immun., 2018-00(0).
PMID: 29203548 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYS Kim et al. (2018-02-20), Activated leukocyte cell adhesion molecule (ALCAM/CD166) regulates T cell responses in a murine model of food allergy Clin. Exp. Immunol., 2018-00(0).
PMID: 29363753 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Szpak et al. (2018-02-19), ?M?2Is Antiatherogenic in Female but Not Male Mice J. Immunol., 2018-00(0).
PMID: 29459405 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMJ Tol et al. (2018-02-17), HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution Autophagy, 2018-00(0):1-13.
PMID: 29455584 -
Species: Mouse
Sample Types: Whole Cells
L Gagnon et al. (2018-02-16), A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84 Am. J. Pathol., 2018-00(0).
PMID: 29454750 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Rossi et al. (2018-02-14), Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis Cell Death Dis, 2018-09(2):250.
PMID: 29445154 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Chen et al. (2018-02-13), SOCS3 deficiency in myeloid cells promotes retinal degeneration and angiogenesis through arginase-1 up-regulation in experimental autoimmune uveoretinitis Am. J. Pathol., 2018-00(0).
PMID: 29452101 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Nishikimi et al. (2018-02-01), Collagen-derived peptides modulate CD4T-cell differentiation and suppress allergic responses in mice Immun Inflamm Dis, 2018-00(0).
PMID: 29388365 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureA Das et al. (2018-01-18), High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages Front Immunol, 2018-09(0):22.
PMID: 29403501 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Lei et al. (2018-01-18), Crucial role of OX40/OX40L signaling in a murine model of asthma Mol Med Rep, 2018-00(0).
PMID: 29344664 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureX Xiao et al. (2018-01-16), Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation J. Exp. Med., 2018-00(0).
PMID: 29339447 -
Species: Mouse
Sample Types: Organoids
Applications: BioassayY Kasagi et al. (2018-01-03), The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial�Changes Cell Mol Gastroenterol Hepatol, 2018-05(3):333-352.
PMID: 29552622 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySN Willis et al. (2017-11-10), Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB Nat Commun, 2017-18(1):1426.
PMID: 29127283 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Bruen et al. (2017-11-06), Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis Cardiovasc Diabetol, 2017-116(1):143.
PMID: 29110715 -
Species: Mouse
Sample Types: Recombinant Protein
Applications: ELISA (Standard)RM Valanparam et al. (2017-10-02), IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection PLoS Pathog., 2017-113(10):e1006647.
PMID: 28968468 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Mroczek et al. (2017-09-20), The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma Nat Commun, 2017-08(1):619.
PMID: 28931820 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Rivera Var et al. (2017-09-15), Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells Nat Commun, 2017-08(1):559.
PMID: 28916785 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDK Chiu et al. (2017-09-11), Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma Nat Commun, 2017-08(1):517.
PMID: 28894087 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Akbar et al. (2017-09-07), Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction JCI Insight, 2017-02(17).
PMID: 28878126 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySMP Vadevoo et al. (2017-09-06), Interleukin 4 receptor-targeted pro-apoptotic peptide blocks tumor growth and metastasis by enhancing anti-tumor immunity Mol. Cancer Ther., 2017-00(0).
PMID: 28878029 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJP Antonios et al. (2017-09-05), Detection of immune responses after immunotherapy in glioblastoma using PET and MRI Proc. Natl. Acad. Sci. U.S.A., 2017-00(0).
PMID: 28874539 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMH Ross et al. (2017-08-30), Bone-induced expression of integrin ?3 enables targeted nanotherapy of breast cancer metastases Cancer Res., 2017-00(0).
PMID: 28855208 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKA Read et al. (2017-08-28), Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4(+) Th Cells J. Immunol., 2017-00(0).
PMID: 28848064 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Hosokawa et al. (2017-08-02), Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function J. Immunol., 2017-00(0).
PMID: 28768723 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRD Vicetti Mi et al. (2017-08-01), IL-4-secreting eosinophils promote endometrial stromal cell proliferation and prevent Chlamydia-induced upper genital tract damage Proc. Natl. Acad. Sci. U.S.A., 2017-00(0).
PMID: 28765368 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Burbage et al. (2017-07-26), The Small Rho GTPase TC10 Modulates B Cell Immune Responses J. Immunol., 2017-00(0).
PMID: 28747344 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Pei et al. (2017-07-11), The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis Sci Rep, 2017-07(1):5107.
PMID: 28698550 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAE Shay et al. (2017-07-06), IL-4 upregulates cyclooxygenase-1 expression in macrophages J. Biol. Chem., 2017-00(0).
PMID: 28684424 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIA Mufazalov et al. (2017-06-29), Balanced Bcl-3 expression in murine CD4(+) T cells is required for generation of encephalitogenic Th17 cells Eur. J. Immunol., 2017-00(0).
PMID: 28598502 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Ye et al. (2017-06-26), TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy J. Immunol., 2017-00(0).
PMID: 28652396 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Huang et al. (2017-06-14), Preferred M2 Polarization by ASC-Based Hydrogel Accelerated Angiogenesis and Myogenesis in Volumetric Muscle Loss Rats Stem Cells Int, 2017-02017(0):2896874.
PMID: 28694827 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Zhu et al. (2017-06-09), miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathway J. Cell. Mol. Med., 2017-00(0).
PMID: 28597963 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYY Sin et al. (2017-05-31), Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency Sci Rep, 2017-07(1):2585.
PMID: 28566761 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Geng et al. (2017-05-15), The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells Nat. Immunol., 2017-00(0).
PMID: 28504697 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Rialdi et al. (2017-05-04), The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity Cell, 2017-0169(4):679-692.e14.
PMID: 28475896 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Lim et al. (2017-04-20), Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry Cell, 2017-0169(3):523-537.e15.
PMID: 28431250 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Park et al. (2017-04-11), CD11b regulates antibody class switching via induction of AID Mol. Immunol., 2017-087(0):47-59.
PMID: 28407558 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Fu et al. (2017-04-11), Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1 J. Exp. Med., 2017-00(0).
PMID: 28400474 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDC Nascimento et al. (2017-04-04), IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population Nat Commun, 2017-08(0):14919.
PMID: 28374774 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySabrina Ceeraz (2017-04-01), VISTA deficiency accelerates the development of fatal murine lupus nephritis Arthritis rheumatology (Hoboken, N.J.), 2017-04-01;0(0).
PMID: 27992697 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Chen et al. (2017-03-29), mTORC2 controls Th9 polarization and allergic airway inflammation Allergy, 2017-00(0).
PMID: 28273354 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCH Son et al. (2017-03-28), Enhancement of antitumor immunity by combination of anti-CTLA-4 antibody and radioimmunotherapy through the suppression of Tregs Oncol Lett, 2017-013(5):3781-3786.
PMID: 28521478 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Minamitani et al. (2017-03-28), Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease Proc. Natl. Acad. Sci. U.S.A, 2017-00(0).
PMID: 28351978 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Mokada-Gop et al. (2017-03-27), Identification of Novel STAT6-Regulated Proteins in Mouse B Cells by Comparative Transcriptome and Proteome Analysis J. Immunol, 2017-00(0).
PMID: 28348271 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Wang et al. (2017-03-24), Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs Theranostics, 2017-07(6):1407-1421.
PMID: 28529626 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayV Piccolo et al. (2017-03-13), Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk Nat. Immunol, 2017-00(0).
PMID: 28288101 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLY Lu et al. (2017-03-13), Pro-inflammatory M1 macrophages promote osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway J. Orthop. Res, 2017-00(0).
PMID: 28248001 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDC Cockrell et al. (2017-03-09), Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages PLoS ONE, 2017-012(3):e0173528.
PMID: 28278296 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Drané et al. (2017-02-27), TIRR regulates 53BP1 by masking its histone methyl-lysine binding function Nature, 2017-0543(7644):211-216.
PMID: 28241136 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Gao et al. (2017-02-17), PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy Sci Rep, 2017-07(0):42846.
PMID: 28211523 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Ng Kuet Le et al. (2017-02-09), Crosstalk between glucocorticoids and IL-4 modulates Ym1 expression in alternatively activated myeloid cells Immunobiology, 2017-00(0).
PMID: 28209270 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Zan et al. (2017-02-08), Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination Nat Commun, 2017-08(0):14244.
PMID: 28176781 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Zhang et al. (2017-01-09), The Crebbp Acetyltransferase is a Haploinsufficient Tumor Suppressor in B Cell Lymphoma Cancer Discov, 2017-00(0).
PMID: 28069569 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBharat Vaidyanath (2016-12-23), The aryl hydrocarbon receptor controls cell-fate decisions in B cells J. Exp. Med, 2016-10(0).
PMID: 28011866 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYee Ling Wu (2016-12-19), Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE J. Exp. Med, 2016-10(0).
PMID: 27994069 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-12-01), Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis Sci Rep, 2016-16(0):37977.
PMID: 27905482 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-11-30), Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-?3 production Proc. Natl. Acad. Sci. U.S.A., 2016-1113(50):E8131-E8140.
PMID: 27911796 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-11-17), Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching Sci Rep, 2016-16(0):37215.
PMID: 27853268 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Ge et al. (2016-11-16), Soluble TNF Regulates TACE via AP-2? Transcription Factor in Mouse Dendritic Cells J. Immunol., 2016-1198(1):417-427.
PMID: 27852742 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-11-15), Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections Sci Rep, 2016-16(0):37211.
PMID: 27845414 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-11-09), Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy J. Immunol., 2016-1197(12):4750-4761.
PMID: 27913649 -
Species: Mouse
Sample Types: Serum
Applications: ELISA (Standard)W Dawicki et al. (2016-10-26), Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3(+)CD49b(-)Foxp3(-) regulatory T�cells J. Allergy Clin. Immunol., 2016-1139(5):1608-1620.e3.
PMID: 28277274 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKazumi Taguchi et al. (2016-10-12), M1/M2-macrophage phenotypes regulate renal calcium oxalate crystal development. Scientific Reports, 2016-10(0):2045-2322.
PMID: 27731368 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-09-20), Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2? J Biol Chem, 2016-00(0).
PMID: 27650501 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-09-06), Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function J Leukoc Biol, 2016-00(0).
PMID: 27601624 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-08-15), Cutting Edge: Marginal Zone Macrophages Regulate Antigen Transport by B Cells to the Follicle in the Spleen via CD21 J Immunol, 2016-00(0).
PMID: 27527595 -
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo(2016-08-11), Role of interleukin-4, the chemokine CCL3 and its receptor CCR5 in neuropathic pain Mol Immunol, 2016-077(0):184-192.
PMID: 27522478 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-07-14), Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status Circ Res, 2016-00(0).
PMID: 27418629 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMakiko Okubo (2016-06-08), M2-polarized macrophages contribute to neovasculogenesis, leading to relapse of oral cancer following radiation Sci Rep, 2016-06(0):27548.
PMID: 27271009 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMithun Maji (2016-06-02), A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells Sci Rep, 2016-06(0):27206.
PMID: 27251373 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAhmed S Elshikha (2016-05-27), Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus PLoS ONE, 2016-011(5):e0156583.
PMID: 27232337 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-05-23), Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription Nat Commun, 2016-07(0):11624.
PMID: 27211851 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-05-19), Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU) PLoS ONE, 2016-011(5):e0155953.
PMID: 27196432 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySchmidt A et al. (2016-05-10), Human macrophages induce CD4(+)Foxp3(+) regulatory T cells via binding and re-release of TGF-beta. Immunol Cell Biol, 2016-094(8):747-62.
PMID: 27075967 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-05-04), Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization J Immunol, 2016-0196(11):4536-43.
PMID: 27183603 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Torres et al. (2016-04-13), IL-12p40/IL-10 Producing preCD8?/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection PLoS Pathog, 2016-012(4):e1005561.
PMID: 27074026 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Shimojima et al. (2016-04-06), Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis J Immunol, 2016-00(0).
PMID: 27053763 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShweta Pasi (2016-03-28), Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response J Biol Chem, 2016-0291(23):12358-69.
PMID: 27022030 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Naik et al. (2016-03-02), Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKC? Kinase Activity J Immunol, 2016-0196(8):3438-51.
PMID: 26936881 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLu G et al. (2016-01-19), Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc Natl Acad Sci U S A, 2016-0113(5):1256-60.
PMID: 26787905 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMasani S et al. (2016-01-19), Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination. Proc Natl Acad Sci U S A, 2016-0113(5):1261-6.
PMID: 26787901 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySasaki C et al. (2015-11-19), p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice. Eur J Immunol, 2015-146(1):212-22.
PMID: 26514620 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAgrawal K et al. (2015-10-16), Protease activity of Per a 10 potentiates Th2 polarization by increasing IL-23 and OX40L. Eur J Immunol, 2015-145(12):3375-85.
PMID: 26417883 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNakatsukasa H et al. (2015-08-31), The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol, 2015-016(10):1077-84.
PMID: 26322481 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDeMicco A et al. (2015-08-28), B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo. J Immunol, 2015-0195(7):3449-62.
PMID: 26320247 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFleming B et al. (2015-06-05), The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. J Leukoc Biol, 2015-098(3):395-407.
PMID: 26048978 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGao F et al. (2015-04-29), Radiation-driven lipid accumulation and dendritic cell dysfunction in cancer. Sci Rep, 2015-05(0):9613.
PMID: 25923834 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOlsan E et al. (2015-04-28), Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease. J Biol Chem, 2015-0290(25):15679-86.
PMID: 25922073 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWalsh N et al. (2015-04-26), LKB1 inhibition of NF-kappaB in B cells prevents T follicular helper cell differentiation and germinal center formation. EMBO Rep, 2015-016(6):753-68.
PMID: 25916856 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen et al. (2015-04-10), Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice. PLoS ONE, 2015-010(4):e0122990.
PMID: 25860995 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRaich-Regue D et al. (2015-04-03), mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo. J Immunol, 2015-0194(10):4767-76.
PMID: 25840913 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLiu X et al. (2015-03-30), Sca-1+Lin-CD117- mesenchymal stem/stromal cells induce the generation of novel IRF8-controlled regulatory dendritic cells through Notch-RBP-J signaling. J Immunol, 2015-0194(9):4298-308.
PMID: 25825436 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNoh K et al. (2015-03-26), Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression. J Biol Chem, 2015-0290(19):12394-402.
PMID: 25814664 -
Species: Mouse
Sample Types: In Vivo
Wakasa Y et al. (2015-03-16), Concentrated protein body product derived from rice endosperm as an oral tolerogen for allergen-specific immunotherapy--a new mucosal vaccine formulation against Japanese cedar pollen allergy. PLoS ONE, 2015-010(3):e0120209.
PMID: 25774686 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLatta C et al. (2015-03-04), Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-beta using BV2 microglial cells and APP/PS1 transgenic mice. J Neuroinflammation, 2015-012(0):41.
PMID: 25885682 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySag D et al. (2015-02-27), The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity. Nat Commun, 2015-06(0):6354.
PMID: 25724068 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKhairnar V et al. (2015-02-18), CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production. Nat Commun, 2015-06(0):6217.
PMID: 25692415 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShan et al. (2015-02-17), Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response. Oncol Lett, 2015-09(4):1549-1556.
PMID: 25788999 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFreeman S et al. (2015-02-03), Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nat Commun, 2015-06(0):6168.
PMID: 25644899 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim J et al. (2015-02-02), Essential engagement of Toll-like receptor 2 in initiation of early protective Th1 response against rough variants of Mycobacterium abscessus. Infect Immun, 2015-083(4):1556-67.
PMID: 25644006 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBrachman R et al. (2015-01-28), Lymphocytes from chronically stressed mice confer antidepressant-like effects to naive mice. J Neurosci, 2015-035(4):1530-8.
PMID: 25632130 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFeldman S et al. (2015-01-26), Constraints contributed by chromatin looping limit recombination targeting during Ig class switch recombination. J Immunol, 2015-0194(5):2380-9.
PMID: 25624452 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHwang I et al. (2015-01-23), An essential role for RGS protein/Galphai2 interactions in B lymphocyte-directed cell migration and trafficking. J Immunol, 2015-0194(5):2128-39.
PMID: 25617475 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBallinger M et al. (2015-01-16), IRAK-M promotes alternative macrophage activation and fibroproliferation in bleomycin-induced lung injury. J Immunol, 2015-0194(4):1894-904.
PMID: 25595781 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLiu K et al. (2015-01-01), Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization. Autophagy, 2015-011(2):271-84.
PMID: 25650776 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWang J et al. (2014-12-09), Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development. Cancer Res, 2014-175(2):306-15.
PMID: 25492861 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRutz S et al. (2014-12-03), Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature, 2014-1518(7539):417-21.
PMID: 25470037 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOeser K et al. (2014-10-22), Conditional IL-4/IL-13-deficient mice reveal a critical role of innate immune cells for protective immunity against gastrointestinal helminths. Mucosal Immunol, 2014-18(3):672-82.
PMID: 25336167 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGhonim M et al. (2014-10-19), DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4(+) T-cell function without causing severe combined immunodeficiency. J Allergy Clin Immunol, 2014-1135(2):425-40.
PMID: 25441643 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBone R et al. (2014-09-11), Inhibition of Ca2+-independent phospholipase A2beta (iPLA2beta) ameliorates islet infiltration and incidence of diabetes in NOD mice. Diabetes, 2014-064(2):541-54.
PMID: 25213337 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHeise N et al. (2014-09-01), Germinal center B cell maintenance and differentiation are controlled by distinct NF-kappaB transcription factor subunits. J Exp Med, 2014-0211(10):2103-18.
PMID: 25180063 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLee S et al. (2014-08-07), A potential protein adjuvant derived from Mycobacterium tuberculosis Rv0652 enhances dendritic cells-based tumor immunotherapy. PLoS ONE, 2014-09(8):e104351.
PMID: 25102137 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPefanis et al. (2014-08-06), Noncoding RNA transcription targets AID to divergently transcribed loci in B cells. Nature, 2014-0514(7522):389-93.
PMID: 25119026 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNeumann C et al. (2014-07-29), Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med, 2014-0211(9):1807-19.
PMID: 25073792 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayColegio O et al. (2014-07-13), Functional polarization of tumour-associated macrophages by tumour-derived lactic acid. Nature, 2014-0513(7519):559-63.
PMID: 25043024 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySahin E et al. (2014-07-11), Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses. J Immunol, 2014-0193(4):1717-27.
PMID: 25015834 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJung I et al. (2014-07-02), Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X. J Immunol, 2014-0193(3):1233-45.
PMID: 24990079 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayStouch A et al. (2014-06-30), IkappaB kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm. J Immunol, 2014-0193(3):1184-93.
PMID: 24981452 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHu et al. (2014-06-30), Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes. Proc Natl Acad Sci U S A, 2014-0111(28):10269-74.
PMID: 24982162 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDowney C et al. (2014-06-18), DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization. PLoS ONE, 2014-09(6):e99988.
PMID: 24940883 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMatthews A et al. (2014-05-30), Binding of AID to DNA does not correlate with mutator activity. J Immunol, 2014-0193(1):252-7.
PMID: 24879790 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDingler F et al. (2014-05-27), Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation. Eur J Immunol, 2014-044(7):1925-35.
PMID: 24771041 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayReynolds C et al. (2014-05-09), Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile. BMC Biol, 2014-012(0):32.
PMID: 24886643 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGabriel T et al. (2014-05-01), Lysosomal stress in obese adipose tissue macrophages contributes to MITF-dependent Gpnmb induction. Diabetes, 2014-063(10):3310-23.
PMID: 24789918 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayRebhandl S et al. (2014-04-15), Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia. Eur J Immunol, 2014-044(7):2175-87.
PMID: 24668151 -
Species: Mouse
Sample Types: Tissue Homogenates
Applications: ELISA (Standard)Shibata T et al. (2014-03-21), Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma. J Immunol, 2014-0192(8):3569-81.
PMID: 24659691 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPark et al. (2014-03-21), Acanthamoeba protease activity promotes allergic airway inflammation via protease-activated receptor 2. PLoS ONE, 2014-09(3):e92726.
PMID: 24658532 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassayvan Solingen C et al. (2014-03-17), Improved repair of dermal wounds in mice lacking microRNA-155. J Cell Mol Med, 2014-018(6):1104-12.
PMID: 24636235 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBezbradica J et al. (2014-03-09), A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat Immunol, 2014-015(4):333-42.
PMID: 24608040 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAl Faraj et al. (2014-03-05), Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI. PLoS ONE, 2014-09(3):e90829.
PMID: 24598763 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNakajima S et al. (2014-03-02), IL-17A as an inducer for Th2 immune responses in murine atopic dermatitis models. J Invest Dermatol, 2014-0134(8):2122-30.
PMID: 24480880 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRamkhelawon B et al. (2014-03-02), Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. Nat Med, 2014-020(4):377-84.
PMID: 24584118 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTaguchi K et al. (2014-02-27), Colony-stimulating factor-1 signaling suppresses renal crystal formation. J Am Soc Nephrol, 2014-025(8):1680-97.
PMID: 24578130 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGarg S et al. (2014-02-25), Aging is associated with increased regulatory T-cell function. Aging Cell, 2014-013(3):441-8.
PMID: 24325345 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySrivastava et al. (2014-02-24), Immunomodulatory glycan lacto-N-fucopentaose III requires clathrin-mediated endocytosis to induce alternative activation of antigen-presenting cells. Infect Immun, 2014-082(5):1891-903.
PMID: 24566617 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTatano Y et al. (2014-02-20), Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization. Sci Rep, 2014-04(0):4146.
PMID: 24553452 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHiroshima Y et al. (2014-02-14), S100A8 induces IL-10 and protects against acute lung injury. J Immunol, 2014-0192(6):2800-11.
PMID: 24532576 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBenasciutti E et al. (2014-02-01), MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity. J Bone Miner Res, 2014-029(2):290-303.
PMID: 24038328 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDufort et al. (2014-01-27), Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation. J Biol Chem, 2014-0289(10):7011-24.
PMID: 24469453 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHan et al. (2014-01-22), Characterization of the structure and immunostimulatory activity of a vaccine adjuvant, de-O-acylated lipooligosaccharide. PLoS ONE, 2014-09(1):e85838.
PMID: 24465739 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAsai H et al. (2014-01-10), Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1. Am J Pathol, 2014-0184(3):808-18.
PMID: 24418258 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDate D et al. (2014-01-02), Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization. J Biol Chem, 2014-0289(15):10318-29.
PMID: 24385430 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTerra R et al. (2013-12-31), To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses. PLoS ONE, 2013-18(12):e82808.
PMID: 24391722 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGarzetti et al. (2013-12-30), Activated macrophages release microvesicles containing polarized M1 or M2 mRNAs. J Leukoc Biol, 2013-10(0).
PMID: 24379213 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayVeremeyko et al. (2013-12-16), IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammation. PLoS ONE, 2013-18(12):e81774.
PMID: 24358127 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLam T et al. (2013-11-25), Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination. PLoS ONE, 2013-18(11):e80414.
PMID: 24282540 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBuchta C et al. (2013-11-20), TRAF5 negatively regulates TLR signaling in B lymphocytes. J Immunol, 2013-1192(1):145-50.
PMID: 24259503 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPereira-Lopes S et al. (2013-11-11), The exonuclease Trex1 restrains macrophage proinflammatory activation. J Immunol, 2013-1191(12):6128-35.
PMID: 24218451 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChattopadhyay et al. (2013-11-11), Antigen-specific induced T regulatory cells impair dendritic cell function via an IL-10/MARCH1-dependent mechanism. J Immunol, 2013-1191(12):5875-84.
PMID: 24218453 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDowdle J et al. (2013-11-07), Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis. PLoS Genet, 2013-19(11):e1003945.
PMID: 24244200 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLeslie K et al. (2013-11-06), Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-kappaB (NF-kappaB): a feed-forward loop for systemic and vascular inflammation. J Biol Chem, 2013-1288(51):36426-36.
PMID: 24196963 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPalm N et al. (2013-10-24), Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Immunity, 2013-139(5):976-85.
PMID: 24210353 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWang X et al. (2013-10-18), TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses. J Immunol, 2013-1191(11):5420-9.
PMID: 24140642 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGao Y et al. (2013-09-26), Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity, 2013-039(4):722-32.
PMID: 24076050 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCao Q et al. (2013-09-18), Failed renoprotection by alternatively activated bone marrow macrophages is due to a proliferation-dependent phenotype switch in vivo. Kidney Int, 2013-085(4):794-806.
PMID: 24048378 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim J et al. (2013-07-03), Mycobacterium tuberculosis RpfB drives Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells. J Leukoc Biol, 2013-094(4):733-49.
PMID: 23825389 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNundel K et al. (2013-06-26), The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells. J Leukoc Biol, 2013-094(5):865-75.
PMID: 23804807 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhao Y et al. (2013-06-14), IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism. J Leukoc Biol, 2013-094(6):1103-12.
PMID: 23772040 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJacome-Galarza C et al. (2013-05-01), Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery. J Bone Miner Res, 2013-028(5):1203-13.
PMID: 23165930 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen M et al. (2013-04-18), Age- and light-dependent development of localised retinal atrophy in CCL2(-/-)CX3CR1(GFP/GFP) mice. PLoS ONE, 2013-08(4):e61381.
PMID: 23637822 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJachetti et al. (2013-04-16), Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses. Oncoimmunology, 2013-02(5):e24520.
PMID: 23762811 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPark J et al. (2013-04-01), p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice. Arthritis Rheum, 2013-065(4):949-59.
PMID: 23280308 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayUmeshappa C et al. (2013-04-01), Differential requirements of CD4(+) T-cell signals for effector cytotoxic T-lymphocyte (CTL) priming and functional memory CTL development at higher CD8(+) T-cell precursor frequency. Immunology, 2013-0138(4):298-306.
PMID: 23113741 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRajaiah R et al. (2013-03-29), Dissociation of endotoxin tolerance and differentiation of alternatively activated macrophages. J Immunol, 2013-0190(9):4763-72.
PMID: 23543762 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGartlan K et al. (2013-03-25), Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration. Eur J Immunol, 2013-043(5):1208-19.
PMID: 23420539 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHwang I et al. (2013-03-22), Rgs13 constrains early B cell responses and limits germinal center sizes. PLoS ONE, 2013-08(3):e60139.
PMID: 23533672 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKnosp C et al. (2013-03-01), Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2. J Immunol, 2013-0190(7):3235-45.
PMID: 23455506 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNapolitano et al. (2013-02-20), Functional education of invariant NKT cells by dendritic cell tuning of SHP-1. J Immunol, 2013-0190(7):3299-308.
PMID: 23427253 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMasani et al. (2013-02-04), Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination. Mol Cell Biol, 2013-033(7):1468-73.
PMID: 23382073 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKumar M et al. (2013-01-09), Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis. J Virol, 2013-087(7):3655-67.
PMID: 23302887 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMabalirajan U et al. (2013-01-01), 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma. Sci Rep, 2013-03(0):1540.
PMID: 23528921 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureXu Q et al. (2012-11-26), Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma. Acta Pharmacol Sin, 2012-133(12):1525-32.
PMID: 23178461 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHou J et al. (2012-10-15), The MSHA Strain of Pseudomonas Aeruginosa Activated TLR Pathway and Enhanced HIV-1 DNA Vaccine Immunoreactivity. PLoS ONE, 2012-17(10):e47724.
PMID: 23077664 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMunich S et al. (2012-10-01), Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands. Oncoimmunology, 2012-11(7):1074-1083.
PMID: 23170255 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAllan RS et al. (2012-07-12), An epigenetic silencing pathway controlling T helper 2 cell lineage commitment. Nature, 2012-0487(7406):249-53.
PMID: 22763435 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2012-07-08), Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat. Med., 2012-01248(0):18.
PMID: 22772464 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPerez-Chacon G et al. (2012-06-18), TNFR-Associated Factor 2 Deficiency in B Lymphocytes Predisposes to Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in Mice. J. Immunol., 2012-0189(2):1053-61.
PMID: 22711886 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2012-06-04), Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A, 2012-0109(25):9971-6.
PMID: 22665806 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCosta MF et al. (2012-05-01), CCL25 induces alpha 4 beta 7 integrin-dependent migration of IL-17+ gamma/delta T lymphocytes during an allergic reaction. Eur. J. Immunol., 2012-042(5):1250-60.
PMID: 22539297 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNoh KT et al. (2012-03-05), Protein kinase C delta (PKCdelta)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia. J. Biol. Chem., 2012-0287(17):14226-33.
PMID: 22393041 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJin W et al. (2011-12-19), The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function. BMC Immunol., 2011-112(0):68.
PMID: 22182253 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKayamuro H et al. (2010-09-29), Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J. Virol., 2010-084(24):12703-12.
PMID: 20881038 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFilardy AA et al. (2010-07-21), Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages. J. Immunol., 2010-0185(4):2044-50.
PMID: 20660352 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYoshizaki A et al. (2010-07-12), Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J. Immunol., 2010-0185(4):2502-15.
PMID: 20624949 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySoderquist RG et al. (2010-06-01), PEGylation of interleukin-10 for the mitigation of enhanced pain states. J Biomed Mater Res A, 2010-093(3):1169-79.
PMID: 19768789 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChang HC et al. (2010-05-02), The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat. Immunol., 2010-011(6):527-34.
PMID: 20431622 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoPerona-Wright G et al. (2010-04-25), Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node. Nat. Immunol., 2010-011(6):520-6.
PMID: 20418876 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJung ID et al. (2010-03-04), Oncostatin M induces dendritic cell maturation and Th1 polarization. Biochem. Biophys. Res. Commun., 2010-0394(2):272-8.
PMID: 20206608 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKotarsky K et al. (2009-10-07), A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa. Mucosal Immunol, 2009-13(1):40-8.
PMID: 19812544 -
Sample Types: N/A
Applications: ELISA (Standard)Wieland CW et al. (2009-03-13), ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis. Microbes Infect., 2009-011(4):524-30.
PMID: 19286469 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayClaudio E et al. (2009-02-01), The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation. J. Immunol., 2009-0182(3):1617-30.
PMID: 19155511 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRichez C et al. (2009-01-15), TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming. J. Immunol., 2009-0182(2):820-8.
PMID: 19124725 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDienz O et al. (2009-01-12), The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. J. Exp. Med., 2009-0206(1):69-78.
PMID: 19139170 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMcKinley L et al. (2008-09-15), TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J. Immunol., 2008-0181(6):4089-97.
PMID: 18768865 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNovitskiy SV et al. (2008-06-17), Adenosine receptors in regulation of dendritic cell differentiation and function. Blood, 2008-0112(5):1822-31.
PMID: 18559975 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWan S et al. (2008-06-01), Direct B cell stimulation by dendritic cells in a mouse model of lupus. Arthritis Rheum., 2008-08(0):1741-50.
PMID: 18512810 -
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In VivoNorman MU et al. (2008-05-01), Interferon-gamma limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism. Eur. J. Immunol., 2008-038(5):1368-80.
PMID: 18412158 -
Sample Types: N/A
Applications: ELISA (Standard)Wieland CW et al. (2008-04-03), CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis. Immunology, 2008-0125(2):272-9.
PMID: 18393969 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySokol CL et al. (2008-03-01), A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat. Immunol., 2008-09(3):310-8.
PMID: 18300366 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoNakamura M et al. (2008-02-02), Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model. Am. J. Pathol., 2008-0172(3):650-8.
PMID: 18245811 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKudlacz E et al. (2007-12-28), The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia. Eur. J. Pharmacol., 2007-1582(1):154-61.
PMID: 18242596 -
Sample Types: N/A
Applications: ELISA (Standard)Maret M et al. (2007-12-01), Liposomal retinoic acids modulate asthma manifestations in mice. J. Nutr., 2007-1137(12):2730-6.
PMID: 18029491 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySeshasayee D et al. (2007-12-01), In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation. J. Clin. Invest., 2007-1117(12):3868-3878.
PMID: 18060034 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKing VL et al. (2007-11-30), Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in mice. Am. J. Pathol., 2007-1171(6):2040-7.
PMID: 18055554 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFranki SN et al. (2007-11-09), Dendritic cells loaded with apoptotic antibody-coated tumor cells provide protective immunity against B-cell lymphoma in vivo. Blood, 2007-1111(3):1504-11.
PMID: 17993615 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZelante T et al. (2007-10-01), IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur. J. Immunol., 2007-137(10):2695-706.
PMID: 17899546 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTian F et al. (2007-09-15), The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation. J. Immunol., 2007-0179(6):3742-51.
PMID: 17785811 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKhaled WT et al. (2007-07-04), The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development. Development, 2007-0134(15):2739-50.
PMID: 17611223 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFritz JH et al. (2007-04-12), Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity, 2007-026(4):445-59.
PMID: 17433730 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAlcaide P et al. (2007-03-29), The 130-kDa glycoform of CD43 functions as an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo. J. Invest. Dermatol., 2007-0127(8):1964-72.
PMID: 17392823 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKoya RC et al. (2007-03-20), Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines. Mol. Ther., 2007-015(5):971-80.
PMID: 17375074 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFujiwara M et al. (2007-03-01), T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways. J. Allergy Clin. Immunol., 2007-0119(3):662-70.
PMID: 17336616 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZheng SG et al. (2007-02-15), IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. J. Immunol., 2007-0178(4):2018-27.
PMID: 17277105 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKitamura K et al. (2007-01-01), Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation. J. Immunol., 2007-0178(1):480-8.
PMID: 17182587 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOgawa K et al. (2006-11-15), Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages. J. Immunol., 2006-1177(10):6787-94.
PMID: 17082592 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChiang YM et al. (2006-10-19), Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator. J Ethnopharmacol, 2006-1110(3):532-8.
PMID: 17101254 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassayde la Fuente MA et al. (2006-07-01), 3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation. Mol. Cell. Biol., 2006-026(14):5214-25.
PMID: 16809760 -
Sample Types: N/A
Applications: ELISA (Standard)Wen H et al. (2006-06-01), Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile. Am. J. Pathol., 2006-0168(6):1940-50.
PMID: 16723709 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLiu Q et al. (2006-05-12), Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation. Biochem. Biophys. Res. Commun., 2006-0345(3):1122-30.
PMID: 16713992 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayButovsky O et al. (2006-03-23), Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis. J. Clin. Invest., 2006-0116(4):905-15.
PMID: 16557302 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoHowell MD et al. (2006-03-01), Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus. Immunity, 2006-024(3):341-8.
PMID: 16546102 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayButovsky O et al. (2005-11-16), Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol. Cell. Neurosci., 2005-131(1):149-60.
PMID: 16297637 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHarrington et al. (2005-10-02), Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol, 2005-16(11):1123-32.
PMID: 16200070 -
Species: Human, Mouse
Sample Types: Whole Cells
Applications: BioassayWei S et al. (2005-02-01), IL-1 mediates TNF-induced osteoclastogenesis. J. Clin. Invest., 2005-0115(2):282-90.
PMID: 15668736 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWada A et al. (2005-01-01), Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines. Anticancer Res., 2005-025(1):299-303.
PMID: 15816551 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDikov MM et al. (2005-01-01), Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation. J. Immunol., 2005-0174(1):215-22.
PMID: 15611243 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBorg C et al. (2004-07-08), NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs. Blood, 2004-0104(10):3267-75.
PMID: 15242871 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBleier JI et al. (2004-06-15), Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow. J. Immunol., 2004-0172(12):7408-16.
PMID: 15187118 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySchleicher U et al. (2004-02-01), Control of Leishmania major in the absence of Tyk2 kinase. Eur. J. Immunol., 2004-034(2):519-29.
PMID: 14768057 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMonick MM et al. (2003-11-15), Intracellular thiols contribute to Th2 function via a positive role in IL-4 production. J. Immunol., 2003-1171(10):5107-15.
PMID: 14607909 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHuaux F et al. (2003-02-15), Dual roles of IL-4 in lung injury and fibrosis. Proteins containing BRCA1 C-terminal (BRCT) domains play crucial roles in response to and repair of DNA damage. Epithelial cell transforming factor ECT2 is a member of the BRCT protein family, but it, 2003-0170(4):2083-92.
PMID: 12574379 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoLarbi KY et al. (2003-01-01), P-selectin mediates IL-13-induced eosinophil transmigration but not eotaxin generation in vivo: a comparative study with IL-4-elicited responses. J. Leukoc. Biol., 2003-073(1):65-73.
PMID: 12525563 -
Sample Types: N/A
Applications: ELISA (Standard)Lukacs NW et al. (2002-04-01), AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity. Am. J. Pathol., 2002-0160(4):1353-60.
PMID: 11943720 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGyotoku E et al. (2001-11-01), The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice. Arch. Dermatol. Res., 2001-1293(10):508-14.
PMID: 11820727 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMorelli AE et al. (2001-09-01), Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation. Blood, 2001-098(5):1512-23.
PMID: 11520802 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGabrilovich DI et al. (1999-10-01), Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. 1537, 1999-15(10):2963-70.
PMID: 10537366
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Customer Reviews for Recombinant Mouse IL-4 Protein (17)
Customer Images
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Application: Cell migration/motilityVerified Customer | Posted 07/25/2023
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Application: Immunoassay StandardVerified Customer | Posted 11/14/2022Used as a standard in our mouse ELISA.
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Application: Enzymatic activity in vitroVerified Customer | Posted 09/29/2021
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Application: CellProlifVerified Customer | Posted 05/20/2021
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 04/13/2021
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 01/27/2021
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Application: CellProlifVerified Customer | Posted 01/05/2021
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Application: CellProlifVerified Customer | Posted 01/05/2021
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Application: CellProlifVerified Customer | Posted 11/09/2020
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Application: In vitro bioactivity in cell cultureReason for Rating: IL-4 was used to differentiate THP-1 into M2 phenotype macrophages. We used immunofluorescence staining to show that after treatment the cells are CD206 positive, which means the treatment is successful in the phenotype change of THP-1 into M2 macrophage.Verified Customer | Posted 10/23/2020concentration :5ng/mlTime: 24 h
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Application: Immune-cell polarization.Verified Customer | Posted 10/06/2020
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 10/16/2019
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Application: CellProlifVerified Customer | Posted 07/13/2018
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 04/02/2018
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Application: Binding assay/Protein-protein interactionReason for Rating: MAB404 binds rhuIL-13Ra2Verified Customer | Posted 02/07/2018
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 07/21/2016We used recombinant mouse IL-4 to polarize bonemarrow-derived macrophages to an "M2" phenotype in vitro. We first generated macrophages from whole bone marrow using MCSF-rich media for 7 days. Then we added IL-4 at 20 ng/ml for 48 hours. Using IL-4R wild-type or knock-out bone marrow, we demonstrated using flow cytometry for an M2 reporter (Arginase1-YFP) that the IL-4 acts through the IL-4 receptor to polarize bone marrow derived macrophages towards the M2 phenotype.
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 01/21/2016
There are no reviews that match your criteria.
FAQs for Recombinant Mouse IL-4 Protein
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Has recombinant mouse IL-4, Catalog # 404-ML, been tested for activity on human cells?
We have not evaluated the bioactivity of Recombinant Mouse IL-4 Protein (Catalog # 404-ML) with human cells. However, we recommend reviewing our list of publications under the Citations tab on the product web page to find reported use of this product with human cells. We do offer a Recombinant Human IL-4 Protein (Catalog # 204-IL), which is suitable for use with human cells.
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What concentration of recombinant mouse IL-4, Catalog # 404-ML, should I use for my cell culture experiment?
We evaluate the bioactivity of Recombinant Mouse IL-4 Protein (Catalog # 404-ML) in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.5-1.5 ng/mL. This ED50 range can provide a starting point for your experiment, but we would recommend end-users perform a dose-response to determine the best concentration for their assay system. We also recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.