Recombinant Bovine CXCL10/IP-10/CRG-2 Protein

Name: Recombinant Bovine CXCL10/IP-10/CRG-2 Protein
Brand: Novus Biologicals
SKU: NBP2-62472

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62472

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Pichia pastoris

Accession #

Q2KIQ8

Conjugate

Unconjugated

Applications

Western Blot, ELISA

View all CXCL10/IP-10/CRG-2 Proteins and Enzymes »

Product Specifications

Description

Recombinant bovine IP-10.

Source:Pichia pastoris

Amino Acid Sequence:aa 20 - 102 of native bovine IP-10, UniProt Q2KIQ8

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

9.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Bovine CXCL10/IP-10/CRG-2 Protein

ELISA: Recombinant Bovine CXCL10/IP-10/CRG-2 Protein [NBP2-62472] -

ELISA: Recombinant Bovine CXCL10/IP-10/CRG-2 Protein [NBP2-62472] - Bovine IP-10 ELISA

Recombinant Bovine IP-10detected using Rabbit anti Bovine IP-10 as the capture reagent and Rabbit anti Bovine IP-10:Biotin as the detection reagent followed by Streptavidin:HRP.

Formulation, Preparation and Storage

NBP2-62472

Preparation Method	Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography.
Formulation	PBS
Preservative	10% Trehalose
Concentration	Lyoph
Reconstitution	Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix vial after reconstitution.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: CXCL10/IP-10/CRG-2

CXCL10/IP-10 is an ELR- angiostatic chemokine that interacts with CXCR3 to attract Th1 cells, eosinophils, monocytes, and NK cells to sites of inflammation. It is upregulated by activated T lymphocytes, neutrophils, splenocytes, keratinocytes, osteoblasts, astrocytes, endothelial cells, smooth muscle cells, and pancreatic beta cells. CXCL10 contributes to disease pathology in many chronic inflammatory disorders including rheumatoid arthritis, psoriasis, cancer, multiple sclerosis, diabetes, and cardiovascular disease.

Alternate Names

CRG-2, CRG2, IP-10

Gene Symbol

CXCL10

UniProt

Q2KIQ8 (Bovine)

Additional CXCL10/IP-10/CRG-2 Products

Product Documents for Recombinant Bovine CXCL10/IP-10/CRG-2 Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Bovine CXCL10/IP-10/CRG-2 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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