TokeOni

Tocris Bioscience, part of Bio-Techne | Catalog # 6555

NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant
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Key Product Details

Description

NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant

Alternative Names

AkaLumine HCl

View all Bioluminescent Substrates Fluorescent Probes and Dyes »

Product Description

TokeOni is a near-infrared red (NIR)-emission luciferin analog. Peak luminescence at 677 nM. ~40-fold brighter than the luciferin-luciferase system in vitro, and 100-1000 times brighter in vivo. Allows non-invasive visualization of single cells deep inside freely moving animals. Ideal for deep tissue applications. Water soluble (<40 mM), orally bioavailable and brain penetrant.

This product is supplied as a hydrochloride salt, the stoichiometry of which is batch dependant. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.

Optical Data

Emission Color Near-IR
λem 677 nm
Application BLI, BTI, Deep Tissue Applications

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Product Specifications

Formula

C16H18N2O2S.xHCl

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

(4S)-2-[(1E,3E)-4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-4,5-dihydro-4-thiazolecarboxylic acid hydrochloride

PubChem ID

124203055

InChI Key

PZCNKVAGZCXXHX-SSRSOBHISA-N

SMILES

CN(C1=CC=C(C=C1)/C=C/C=C/C2=N[C@@H](C(O)=O)CS2)C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 5mg/ml in water with gentle warming and to 10mg/ml in DMSO

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Background References

References are publications that support the biological activity of the product.

Product Documents for TokeOni

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TokeOni

For research use only

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