ICG-d7
Tocris Bioscience, part of Bio-Techne | Catalog # 7749
Near-infrared (NIR) fluorescent dye; partially deuterated form of Indocyanine Green (Cat. No. 7510), suitable for in vivo imaging.
Discontinued Product
7749 has been discontinued.
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Key Product Details
Description
Near-infrared (NIR) fluorescent dye; partially deuterated form of Indocyanine Green (Cat. No. 7510), suitable for in vivo imaging.
Product Description
Key information: ICG-d7 is a partially deuterated form of near-infrared fluorescent dye Indocyanine Green (ICG; Cat. No. 7510).Application: Fluorescence microscopy, in vivo imaging.
Properties and Photophysical Data: ICG-d7 operates in the 700 - 900 nm wavelength range; also exhibits fluorescence emission in the shortwave infrared window (SWIR; 1,000 - 2,000 nm) which enables in vivo imaging. ICG-d7 shows improved stability in aqueous solutions over ICG with the same fluorescence brightness, and similar absorption and emission maxima in both DMSO and FBS. Excitation and emission maxima (λ) are 794 nm and 818 nm, respectively; quantum yield = 0.21; extinction coefficient = 228,000 M-1cm-1.
Licensing Information
Sold under license from the University of Notre DameOptical Data
| Emission Color | Near-IR |
| λabs | 794 nm |
| λem | 818 nm |
| Extinction Coefficient (ε) | 228000 M-1cm-1 |
| Quantum Yield (φ) | 0.21 |
| Application | Fluorescence Microscopy, In Vivo Imaging |
| Alternative For | Indocyanine green |
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Product Specifications
Molecular Weight
782.01
Formula
C43H40D7N2O6S2Na
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
Sodium 4-(2-((1E,3E,5E,7Z)-7-(1,1-Dimethyl-3-(4-sulfonatobutyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)hepta-1,3,5-trien-1-yl-1,2,3,4,5,6,7-d7)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate
CAS Number
2861905-57-7
InChI Key
MOFVSTNWEDAEEK-ZMRQXZMGSA-M
SMILES
CC1(C)/C(N(CCCCS(=O)(O[Na])=O)C2=C1C3=CC=CC=C3C=C2)=C(/C([2H])=C(/C([2H])=C(/C([2H])=C(C4=[N+](CCCCS([O-])(=O)=O)C5=C(C6=CC=CC=C6C=C5)C4(C)C)\[2H])[2H])[2H])[2H]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 7.82 | 10 | |
| DMSO | 7.82 | 10 |
Preparing Stock Solutions
for ICG-d7
The following data is based on the product molecular weight 782.01
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.79 mL | 63.94 mL | 127.88 mL |
| 0.5 mM | 2.56 mL | 12.79 mL | 25.58 mL |
| 1 mM | 1.28 mL | 6.39 mL | 12.79 mL |
| 5 mM | 0.26 mL | 1.28 mL | 2.56 mL |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Li and Smith Deuterated indocyanine green (ICG) with extended aqueous storage shelf-life: chemical and clinical implications. Chemistry 2021 PMID: 34403531
Product Specific Notices for ICG-d7
For research use only
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