Cyanine 5.5, SE

Name: Cyanine 5.5, SE
Brand: Tocris Bioscience
SKU: 7431

Tocris Bioscience, part of Bio-Techne | Catalog # 7431

COA / SDS

Far red fluorescent dye for the labeling of amines; supplied as NHS ester

Discontinued Product

7431 has been discontinued. View all Fluorescent Dyes products.

Key Product Details

Description:	Far red fluorescent dye for the labeling of amines; supplied as NHS ester
Alternative Names:	Cy5.5,Sulpho-Cyanine 5.5
Chemical Name:	Tris(triethylammonium) 3-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-2-((1E,3E,5Z)-5-(3-ethyl-1,1-dimethyl-6,8-disulfonato-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-6,8-disulfonate
Purity:	≥90% (HPLC)
Molecular Weight:	1317.7

View Full Technical Details for Cyanine 5.5, SE

Technical Data
Citations

Biological Activity for Cyanine 5.5, SE

Cyanine 5.5, SE is a far red fluorescent dye for the labeling of amines. Cyanine 5.5, SE is ideal for labeling antibodies, peptides, glycoproteins, and amine-rich proteins. Cyanine 5.5, SE is also suitable for in vivo imaging. Excitation maximum ~675 nm; emission maximum ~694 nm.

Optical Data for Cyanine 5.5, SE

Emission Color	Far Red
λ_abs	675 nm
λ_em	694 nm
Extinction Coefficient (ε)	190000 M^-1cm^-1
Quantum Yield (φ)	0.28
Reactive Group	NHS ester
Application	labeling antibodies, peptides, glycoproteins, and amine-rich proteins - suitable for in vivo imaging
Alternative For	Alexa Fluor^® 680, and DyLight 680

Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company.

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Technical Data for Cyanine 5.5, SE

M. Wt	1317.7
Formula	C₄₅H₄₄N₃O₁₆S₄.3C₆H₁₅NH
Storage	Store at -20°C
Purity	≥90% (HPLC)
InChi Key	GECMOSJJYVCJFX-UHFFFAOYSA-N
Smiles	CCN1C2=C(C(C)(/C1=C/C=C/C=C/C3=[N+](C4=C(C3(C)C)C5=CC(S([O-])(=O)=O)=CC(S([O-])(=O)=O)=C5C=C4)CCCCCC(ON6C(CCC6=O)=O)=O)C)C7=CC(S([O-])(=O)=O)=CC(S([O-])(=O)=O)=C7C=C2.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Cyanine 5.5, SE

References are publications that support the biological activity of the product.

Kim Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging. J.Am.Chem.Soc. 2006 PMID: 16536501
Weissleder In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat.Biotechnol 1999 PMID: 10207887
Ma Ultrasmall sub-10 nm near-infrared fluorescent mesoporous silica nanoparticles. J.Am.Chem.Soc. 2012 PMID: 22830608