CELT-211
Tocris Bioscience, part of Bio-Techne | Catalog # 7953
Fluorescent serotonin 5HT2B receptor ligand for HTS
Key Product Details
Description
Fluorescent serotonin 5HT2B receptor ligand for HTS
Product Description
CELT-211 is a potent and selective fluorescent h5HT2B serotonin receptor ligand. It shows full selectivity for h5HT2B over h5HT2A, h5HT2C (Ki values is 56.3 nM for h5HT2B receptors in radioligand binding assay). Excitation and emission maxima (λ) are 589 and 616 nm, respectively. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.Add 82 μL of assay buffer containing 1% of DMSO to obtain a 100 μM stock solution, and use 250 nM as a working concentration.
Scientific Data Images for CELT-211
Application of CELT-211 in CHO cells expressing the human 5HT2BR.
CHO cells expressing the human 5HT2BR labelled with CELT-211 (pink) at 56 nM and Hoechst 33342 (blue) (catalog # 5117) without (A) or with (B) 5-HT (50 µM) preincubation.Licensing Information
Sold under license from Celtarys ResearchOptical Data
| λabs | 589 nm |
| λem | 616 nm |
| Application | Time-resolved fluorescence energy transfer (TR-FRET) |
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Product Specifications
Molecular Weight
1330.22
Storage
Store at -20°C
Purity
≥95% (HPLC)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Product Specific Notices for CELT-211
For research use only
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